PhD Position in Biochemistry and Molecular Biology: ZNF768 and Cell Cycle Regulation
Investigate the role of the transcription factor ZNF768 in cell cycle progression, genome stability, and lung cancer.
Best for:Best for candidates with an MSc in molecular or cell biology and a strong interest in transcriptional regulation and cancer mechanisms.
Overview
The ELOWE Lab at Université Laval is seeking a motivated PhD candidate to study the function of ZNF768, a fast-evolving zinc-finger transcription factor. This research aims to elucidate how ZNF768 regulates cell cycle progression, maintains genome stability, and contributes to lung adenocarcinoma development. The successful applicant will employ advanced techniques including high-resolution live-cell imaging, mutagenesis, and bioinformatics. This position offers the opportunity to work within a dynamic oncology research environment at the CR-CHU de Québec.
What you'll do
- Investigate the impact of ZNF768 loss on G0 exit and cell cycle progression.
- Analyze the mechanisms by which ZNF768 overexpression promotes uncontrolled cell proliferation.
- Define the functional role of ZNF768 in the progression of lung adenocarcinoma.
- Perform high-resolution and live-cell imaging experiments.
- Conduct mutagenesis studies to explore protein function.
- Apply bioinformatics tools to analyze transcriptional data.
- Communicate research findings effectively in both French and English.
Requirements
Degree required: MSc in molecular biology, cell biology, biochemistry, or a related field
Degree offered: PhD
Language: Proficiency in French and English
Instruction: French and English
- Strong academic record
- Proficiency in molecular and cell biology techniques
- Scientific writing skills
- Ability to communicate in French and English
- Must hold or expect to complete an MSc in a relevant discipline
Funding & terms
How to apply
Deadline: 2026-12-01
Interested candidates should apply through the official portal. Only shortlisted candidates will be contacted for interviews.
- CV
- Academic transcripts
- Cover letter
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