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Computational Biology and Information Theory● OpenPreview

PhD Position: Robust Data Retrieval for DNA-Based Data Storage (RobDNA)

Develop innovative algorithms for robust data retrieval in DNA-based storage systems to address challenges in error correction and compression.

Best for:Best for candidates with a strong background in signal/image processing, optimization, and programming, and an interest in information theory and source coding.

Inria · Rennes, France · R1 · First-stage researcher
More professors at Inria
DNA-based data storageError correction algorithmsCompression techniques for DNA dataNanopore sequencing challengesNon-binary channel codingQuaternary alphabet optimization
Deadline
Nov 20, 2026
36 days
Funding
Salaried
€2.3k/mo
Start date
2026-12-01
Full-time
Location
Rennes
France

Overview

This PhD position at Inria’s Rennes Centre focuses on advancing DNA-based data storage by designing algorithms for robust data retrieval. With global data volumes projected to reach 180 zettabytes annually, traditional storage technologies struggle to scale sustainably. DNA storage offers unparalleled density, longevity, and energy efficiency, but practical implementation requires overcoming key challenges like error-prone sequencing and data reconstruction. The project will explore hybrid approaches combining constrained DNA sequences with error-correction techniques tailored for nanopore sequencing, leveraging quaternary alphabet properties and integrating compression algorithms. The work will build on non-binary channel coding and DNA-specific transcoding, aiming to enable scalable, accurate DNA data retrieval.

DNA data storageerror correctioncompression algorithmsnanopore sequencinginformation theoryquaternary codingrobust data retrievalbiocomputing

What you'll do

  • Develop algorithms for robust data retrieval in DNA-based storage systems, focusing on error correction and compression.
  • Design constrained DNA sequences to minimize sequencing errors while enabling efficient error correction.
  • Integrate compression and error-correction mechanisms tailored for nanopore sequencing technologies.
  • Explore hybrid approaches combining constrained coding and error-correction strategies.
  • Leverage quaternary alphabet properties to optimize data encoding and retrieval processes.
  • Collaborate with researchers to validate algorithms using nanopore sequencing data.
  • Publish findings in peer-reviewed journals and present results at international conferences.

Requirements

Degree required: Master's degree (Bac+5) or equivalent in Computer Science, Signal/Image Processing, or a related field

Degree offered: PhD

Language: English (proficiency required for academic work and communication)

Instruction: English

Required skills
  • Strong background in image/signal processing
  • Proficiency in optimization techniques
  • Programming skills (preferably in Python, C++, or similar)
  • Knowledge of source coding and information theory
  • Experience with algorithm design and implementation
Nice to have
Familiarity with DNA data storage researchExperience with error correction algorithmsKnowledge of nanopore sequencing technologies
Eligibility
  • No specific nationality or residency restrictions mentioned
  • Open to all applicants meeting academic requirements

Funding & terms

Type
Salaried
Amount
€2.3k/mo
Duration
3 years
Programme
Inria
Inria

How to apply

Deadline: 2026-11-20

Applicants must submit their CV, cover letter, and letters of recommendation online through the Inria application portal. Ensure all documents are uploaded before the deadline. Applications sent via other channels are not guaranteed to be processed.

Documents required
  • CV
  • Cover letter
  • Letters of recommendation (optional)
↗Apply on site

Contact

Aline Roumy· PhD Supervisor

aline.roumy@inria.fr

AR
Prof.
Aline Roumy
Centre at Rennes University
Lab
COMPACT
Inria
France
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