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Intelligent Systems Engineering● OpenResearch staffPreview

Assistant Scientist - AI-Enabled Immune Digital Twin Workflows

Build reproducible, data-assimilating immune digital twin workflows and forecasting pipelines at Indiana University Bloomington.

Best for:Best for computational scientists and software engineers with a background in mechanistic modeling and data assimilation.

Indiana University Bloomington · Bloomington, United States · R2 · Recognised researcher
More professors at Indiana University Bloomington
Digital TwinsData AssimilationMechanistic ModelingComputational BiologySoftware Engineering
This is a research staff position — not a PhD studentship.Non-tenure
Deadline
—
Funding
Salaried
$100k/yr
Start date
flexible
Full-time
Location
Bloomington
United States

Overview

Indiana University Bloomington invites applications for an Assistant Scientist position within the Intelligent Systems Engineering department. Working under the direction of Dr. James A. Glazier, the successful candidate will focus on building reproducible, testable, and sequential data-assimilating digital twin workflows. Responsibilities include implementing patient-specific forecasting and rebasing pipelines, designing anomaly-detection logic, and integrating workflows with national consortium platforms. Candidates are expected to bring a strong background in mechanistic modeling, software engineering, and computational biomedical sciences.

Digital TwinData AssimilationPythonMechanistic ModelingIntelligent SystemsImmunology

What you'll do

  • Develop Python workflows for short-horizon forecasting and patient-specific rebasing
  • Implement data-assimilation methods including Kalman and Bayesian updating techniques
  • Design anomaly detection and missing-information inference logic for biological systems
  • Build reproducible computational packages incorporating CI/CD, containerization, and testing
  • Manage complex model ensemble interfaces and coordinate infrastructure with consortium collaborators
  • Integrate research workflows with external consortium platforms such as Vivarium and QSP
  • Write and contribute to technical publications detailing the research outcomes

Requirements

Degree required: PhD or equivalent terminal degree in a quantitative, computational, or biomedical discipline

Language: English proficiency for professional and technical communication

Instruction: English

Publications: Track record of writing technical publications as evidenced by research background

Required skills
  • Programming proficiency in Python, Julia, R, or MATLAB
  • Demonstrated background in mechanistic modeling such as ODEs, dynamical systems, QSP, or agent-based models
  • Familiarity with inflammation, cytokine signaling, sepsis, or critical care biology
  • One year of successful postdoctoral research experience
Nice to have
Experience with data assimilation methods like Kalman filtering or Bayesian updatingExperience with software engineering practices including CI/CD and containerization
Eligibility
  • Hold a PhD or equivalent terminal degree
  • Possess at least one year of postdoctoral research experience

Funding & terms

Type
Salaried
Amount
$100k/yr
Duration
—
Programme
Indiana University Bloomington
Indiana University Bloomington

How to apply

Deadline: 2026-11-02

Interested applicants should submit their application materials through the designated external application portal. For any questions regarding the position, please contact Professor James Glazier directly via email.

Documents required
  • CV
  • Cover letter
↗Apply via form

Contact

James Glazier· Professor

glazier@iu.edu

JG
Prof.
James Glazier
Intelligent Systems Engineering
Lab
Intelligent Systems Engineering
Indiana University Bloomington
United States
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