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Chemistry and Synthetic Biology● Open★ EU-FUNDEDPreview

PhD Researcher Positions – ERC Advanced Grant ProtoEco

Join an interdisciplinary team pioneering biohybrid micro-communities between artificial and living cells.

Best for:Best for interdisciplinary researchers with a background in chemistry, materials science, or biology interested in synthetic life.

University of Mainz · Mainz, Germany · R1 · First-stage researcher
More professors at University of Mainz
Synthetic BiologyArtificial CellsBiomaterialsDNA NanoscienceSystems ChemistryCell-Material Interfaces
Deadline
Nov 30, 2026
46 days
Funding
—
not specified
Start date
flexible
Full-time
Location
Mainz
Germany

Overview

The Walther Lab at Johannes Gutenberg University Mainz is seeking motivated PhD researchers for the ERC Advanced Grant project 'ProtoEco'. This project explores the intersection of systems chemistry, DNA nanoscience, and cell biology to create interactive communities of artificial and mammalian cells. Successful candidates will contribute to developing biohybrid systems capable of metabolic coupling, signal processing, and adaptive behavior. The position offers a collaborative, international environment with access to state-of-the-art facilities and opportunities for high-impact research.

Synthetic CellsBiohybrid SystemsMetabolic CouplingMolecular ComputingTissue EngineeringAdaptive MaterialsMicrofluidics

What you'll do

  • Design and synthesize polymer-based artificial cell platforms with tunable responsiveness.
  • Engineer DNA-based circuits for molecular signal processing and sensing.
  • Develop and characterize biohybrid co-culture systems involving mammalian cells.
  • Perform quantitative analysis using advanced fluorescence and confocal microscopy.
  • Construct metabolic interaction maps to study communication between synthetic and living matter.
  • Contribute to the development of adaptive therapeutic systems and homeostatic signaling models.
  • Collaborate with interdisciplinary team members to integrate chemical and biological modules.

Requirements

Degree required: Master's degree or equivalent in Chemistry, Biology, Engineering, or a related field.

Degree offered: PhD

Language: English; excellent proficiency required.

Instruction: English

Required skills
  • Strong background in chemistry, materials science, or biological engineering.
  • Experience with experimental research in a laboratory setting.
  • Excellent proficiency in English, both written and spoken.
  • Ability to work independently and collaboratively in an interdisciplinary team.
Nice to have
Experience with microfluidics or cell culture techniques.Knowledge of DNA nanotechnology or molecular computing.Proficiency in advanced microscopy and image analysis.Experience with enzymatic reaction networks or metabolic engineering.
Eligibility
  • Must hold a Master's degree or equivalent at the time of appointment.

Funding & terms

Type
Unknown
Amount
—
Duration
not specified
Programme
Horizon Europe - ERC
EU-FUNDEDEuropean Research Council

How to apply

Deadline: 2026-11-30

Interested candidates should submit their application materials directly to the contact email provided. Ensure all required documents are included to be considered for the position.

Documents required
  • CV
  • Cover letter
  • Academic transcripts
✉Apply by email

Contact

Andreas Walther· Principal Investigator

andreas.walther@uni-mainz.de

https://www.walther-group.com

AW
Prof.
Andreas Walther
Chemistry
Lab
Walther Lab
University of Mainz
Horizon Europe - ERCGermany
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