PhD Position in Human Liver Organoid Modelling
Join a pioneering research group to explore human liver function and disease.
Best for:Best for candidates with a strong background in molecular biology and a passion for liver research.
Overview
The Artegiani & Hendriks group at the Princess Máxima Center is seeking a dedicated PhD candidate to investigate the mechanisms of human liver function and disease through innovative in vitro model development. This four-year project will utilize human organoids, CRISPR-Cas tools, and advanced imaging techniques to study metabolic dysfunction-associated liver diseases. Candidates should be motivated scientists with a strong background in molecular and cellular biology, eager to contribute to significant research in liver biology. The position offers a unique opportunity to work in an international and multidisciplinary environment focused on pediatric oncology.
What you'll do
- Develop and optimize in vitro models of human liver function using organoids.
- Conduct mechanistic studies to understand liver disease progression.
- Utilize CRISPR-Cas tools for gene editing in liver organoids.
- Perform -omic analyses, including scRNA-sequencing.
- Collaborate with multidisciplinary teams in an international research setting.
- Present research findings at conferences and in publications.
Requirements
Degree required: MSc in Molecular Biology, Cellular Biology, or a related field
Degree offered: PhD
Language: English; Excellent proficiency required
Instruction: English
- Strong background in molecular and cellular biology
- Experience with in vitro model development
- Familiarity with CRISPR-Cas technology
- Ability to work independently and collaboratively
- Must have completed a Master's degree
- Open to international candidates
Funding & terms
How to apply
Deadline: 2026-11-29 (Europe/Amsterdam) · open until filled
Interested candidates should submit an up-to-date resume, a short motivation letter (maximum two pages), and contact information for 2-3 references. Incomplete applications will not be considered.
- CV
- Motivation letter
- Contact information of references
Contact
Benedetta Artegiani and Delilah Hendriks· Supervisors
b.a.artegiani@prinsesmaximacentrum.nl, d.f.g.hendriks-7@prinsesmaximacentrum.nl
Create a free profile to unlock your personal match score, the full requirements, funding details and how to apply — in English or Persian.