PhD Studentship in Obstetric Antiphospholipid Syndrome
Investigate mechanisms of obstetric antiphospholipid syndrome and placental injury through multidisciplinary translational research.
Best for:Best for candidates with a background in biomedical sciences or immunology seeking a translational research PhD.
Overview
This PhD studentship is hosted within the Department of Ageing, Rheumatology and Regenerative Medicine at the UCL Division of Medicine. The successful candidate will investigate the molecular and cellular mechanisms underlying obstetric antiphospholipid syndrome and its associated pregnancy complications. Working within a multidisciplinary team alongside clinicians and scientists, the student will employ cutting-edge laboratory and computational methods to analyze patient cohorts. The role offers comprehensive training, access to state-of-the-art facilities, and collaborative opportunities with external institutions such as the Wellcome Sanger Institute.
What you'll do
- Investigate how specific antiphospholipid antibodies drive inflammation at the maternal-fetal interface and cause placental dysfunction.
- Perform advanced flow cytometry and immune cell phenotyping on clinical samples.
- Execute cell culture and functional immunology assays to evaluate immune pathways.
- Isolate and characterize immune complexes and conduct ELISA and biomarker discovery.
- Utilize multiplex tissue imaging and spatial biology techniques such as Cell-DIVE.
- Collaborate closely with clinicians, scientists, and patient partners to analyze well-characterised patient cohorts.
Requirements
Degree required: First-class BSc or Master's degree in biomedical sciences, immunology, microbiology, or a related field
Degree offered: PhD
Language: English
Instruction: English
- Strong academic background in biomedical sciences, immunology, microbiology, or a related field
- Commitment to careful data analysis and safe handling of human biological samples
- Strong organizational, problem-solving, and communication skills
- Readiness to work flexibly across UCL and the Wellcome Sanger Institute
Funding & terms
How to apply
For informal enquiries, contact Dr Muhammad Shipa via email. Review the available project description document and submit application materials according to the institutional guidelines.
- CV
- Studentship project description
Contact
Muhammad Shipa· Dr
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