Research Fellow in Electron Microscopy

The University of Birmingham is seeking a Research Fellow to join the integrative structural biology group led by Prof. Teresa Carlomagno. The successful candidate will utilize state-of-the-art infrastructure, including a newly acquired FEI Glacios 3 Cryo-Electron Microscope, to investigate the functional mechanisms of biomolecular complexes. The role involves applying cryo-EM and complementary techniques to study RNA metabolism and gene regulation. Applicants are expected to contribute to experimental design, data analysis, and the dissemination of research findings through high-impact publications.

• Develop and execute research objectives aligned with the laboratory's structural biology program.
• Operate and maintain the cryo-EM microscope for high-resolution data acquisition.
• Perform image processing, 3D reconstruction, and structural analysis of cryo-EM data.
• Produce and purify biomolecular complexes using molecular biology and biochemical techniques.
• Optimize sample preparation and cryo-EM grid preparation protocols.
• Disseminate research findings through peer-reviewed publications and conference presentations.
• Supervise and mentor PhD students and junior researchers.
• Contribute to the preparation of research funding applications.