Technical Specialist - Mass Spectrometry Imaging
Lead MALDI mass spectrometry tissue imaging and multi-omics research at King's College London.
Best for:Best for researchers with a PhD and hands-on MALDI mass spectrometry imaging experience in a life sciences setting.
Overview
King's College London is seeking a dedicated Technical Specialist to join the King's Smart Trials Hub within the Research Platforms Office. The role focuses on leading all aspects of MALDI mass spectrometry tissue imaging, specifically analyzing spatially resolved metabolites, lipids, and proteins using advanced Bruker systems. The successful candidate will optimize tissue sectioning, develop matrix application protocols, and perform complex data analysis for various academic and commercial research projects. This is a full-time, facility-based indefinite contract position requiring strong technical expertise and collaborative skills in a laboratory environment.
What you'll do
- Lead all aspects of MALDI mass spectrometry tissue imaging using the Bruker timsTOF Flex MALDI-2 system
- Optimize tissue sectioning and develop matrix application protocols to maintain spatial integrity
- Design acquisition methods for detailed spatially resolved single cell and multi-sample analyses
- Perform complex data analysis, annotation, and quality control across metabolites, lipids, and proteins
- Provide technical guidance, training, and support to laboratory users and multidisciplinary project teams
- Maintain accurate records and documentation in compliance with quality assurance and control standards
Requirements
Degree required: PhD in chemistry, life sciences, or a relevant subject area (or equivalent research experience)
Language: English; excellent written and verbal proficiency
Instruction: English
- Hands-on experience with MALDI mass spectrometry imaging equipment and method development
- Proficiency in sample preparation, including matrix delivery protocols for tissue analysis
- Demonstrated data acquisition and analysis skills for spatially resolved metabolites and lipids
- Proven ability to work independently, manage competing demands, and meet deadlines
- Experience maintaining quality assurance and quality control standards in a research laboratory
- Strong communication and presentation skills for technical and scientific reporting
- Candidates who have submitted their thesis and are awaiting their PhD award will be considered for appointment as a Research Assistant until confirmation of the degree.
Funding & terms
How to apply
Deadline: 2026-11-01
Applications must be submitted online through the King's College London recruitment portal. Candidates should provide all requested application materials and documentation addressing the essential and desirable criteria before the deadline.
- CV
- Job Description application form
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