MSCA Doctoral Network PhD position: Computational design of novel β-catenin binders

This PhD position is part of the MSCA Doctoral Network at the Technical University of Vienna, focusing on the computational design of novel β-catenin binders. The project aims to create specific binders that modulate β-catenin activity, utilizing advanced machine learning protocols and structural modeling. Candidates will engage in a collaborative research environment, contributing to the development of high-affinity binders for targeted modulation of β-catenin. Successful applicants will have the opportunity to work with leading researchers and gain valuable experience in both computational and experimental methodologies.

• Design specific binders for β-catenin using computational methods.
• Utilize machine learning protocols to enhance binder efficacy.
• Collaborate with other researchers in the network to refine designs.
• Conduct experiments to validate binding interactions.
• Analyze data from structural and proteomic studies.
• Participate in training and development activities within the doctoral network.