Postdoctoral Research Fellow in Molecular Mechanisms of Eukaryotic Transcription

The School of Life Sciences at the University of Sussex seeks an ambitious Postdoctoral Research Fellow to join a vibrant research group investigating the molecular mechanisms of eukaryotic transcription. The successful candidate will explore how reversible phosphorylation of key factors coordinates RNA polymerase II transcription with RNA processing and maturation. The role combines mammalian cell culture, genome editing, biochemistry, and functional genomics within a collaborative and interdisciplinary environment. Applicants are expected to drive independent experimental ideas, contribute to a broader multidimensional research programme, and demonstrate strong scientific curiosity.

• Maintain mammalian cell culture and generate degron-tagged cell lines.
• Conduct state-of-the-art transcriptome and functional genomic analyses.
• Perform biochemical assays to reconstitute transcription in vitro and analyze protein-RNA or protein-protein interactions.
• Design and execute complementary experimental approaches to elucidate molecular mechanisms.
• Contribute to collaborative research goals while developing independent scientific ideas.