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Neuroscience● OpenPreview

PhD Position: Studying Neural Circuits for Flexible Memory Formation in Drosophila

Explore the neural mechanisms of flexible memory in Drosophila larvae using genetic, behavioral, and two-photon imaging techniques.

Best for:Best for neuroscientists with hands-on experience in Drosophila genetics, calcium imaging, and behavioral neuroscience, interested in computational and systems-level approaches to memory and learning.

Institut des Neurosciences Paris-Saclay · Saclay, France · R1 · First-stage researcher
More professors at Institut des Neurosciences Paris-Saclay
neural circuits in memory formationDrosophila melanogaster as a model organismassociative learning mechanismsin vivo calcium imaginggenetic manipulation of neural pathwaysrecurrent neural networks in behavior
Deadline
Oct 13, 2026
Expired
Funding
Salaried
€2.3k/mo
Start date
2026-11-01
Full-time
Location
Saclay
France

Overview

This PhD position at the Institut des Neurosciences Paris-Saclay focuses on investigating the neural circuits underlying flexible memory formation in *Drosophila melanogaster* larvae. The project combines behavioral experiments, genetic manipulation, and advanced in vivo calcium imaging to dissect how recurrent neural circuits contribute to associative learning and memory. The successful candidate will work within a multidisciplinary team studying reinforcement learning principles at the neurobiological level, leveraging cutting-edge tools like two-photon microscopy and connectome data. The position is ideal for neuroscientists with hands-on experience in Drosophila and imaging techniques, seeking to advance fundamental understanding of neural plasticity and decision-making.

neuroscience PhDDrosophila memory researchtwo-photon imagingneurogeneticsbehavioral neurosciencecalcium imagingassociative learningneural plasticity

What you'll do

  • Conduct literature reviews and analyze scientific publications to inform experimental design.
  • Design and execute genetic crosses in *Drosophila melanogaster* to manipulate neural circuits.
  • Plan and perform behavioral experiments to study associative learning and memory formation.
  • Set up and conduct in vivo calcium imaging using two-photon microscopy to monitor neuronal activity.
  • Analyze and interpret experimental data, including statistical and computational methods.
  • Maintain rigorous lab notebooks and organize research data systematically.
  • Present and discuss research findings regularly within the team and at scientific conferences.
  • Author and present scientific publications based on research outcomes.

Requirements

Degree required: Master’s degree (or equivalent) in neuroscience or a related field

Degree offered: PhD

Language: English; proficiency required for scientific communication and collaboration

Instruction: French and English

Required skills
  • Hands-on experience with *Drosophila melanogaster* genetic models
  • Familiarity with calcium imaging techniques (confocal or two-photon microscopy)
  • Strong background in behavioral neuroscience experiments
  • Basic proficiency in statistical analysis and programming (Python or MATLAB)
  • Excellent written and spoken scientific English
Nice to have
Experience with connectome data analysisPrior exposure to reinforcement learning modelsFamiliarity with advanced imaging software (e.g., ImageJ, Fiji)
Eligibility
  • Open to all nationalities
  • No residency restrictions
  • No age limit
  • No prior experience cap beyond Master’s degree

Funding & terms

Type
Salaried
Amount
€2.3k/mo
Duration
3 years (standard PhD duration)
Programme
ANR (Agence Nationale de la Recherche) funding
ANR (Agence Nationale de la Recherche)

How to apply

Deadline: 2026-10-13

Applicants must submit their application through the CNRS employment portal. The application should include a CV, a cover letter, and any relevant academic transcripts or certificates. Additional documents may be requested upon review.

Documents required
  • CV
  • Cover letter
  • Master’s degree transcripts
  • Proof of English proficiency (if applicable)
↗Apply on site

Contact

CNRS Employment Office· Recruitment Contact

https://emploi.cnrs.fr

FL
Prof.
First Last
Neurobiologie moléculaire et cellulaire / Neurophysiologie
Lab
Circuits récurrents, apprentissage et mémoire
Institut des Neurosciences Paris-Saclay
ANR (Agence Nationale de la Recherche) fundingFrance
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