Postdoctoral Fellow in Developmental Signalling
Investigate cell fate specification and mitotic erasure in early vertebrate development at the Francis Crick Institute.
Best for:Best for postdoctoral researchers with expertise in zebrafish embryology, live imaging, and cell signalling dynamics.
Overview
The Francis Crick Institute invites applications for a four-year Postdoctoral Fellow position in the Developmental Signalling Laboratory, led by Caroline Hill. The research focuses on understanding how endoderm and mesoderm progenitors are specified in early zebrafish embryos, specifically examining the interplay between Nodal and FGF/Erk signalling and cell cycle dynamics, including mitotic erasure. The successful candidate will lead their own research project, collaborate with team members and external partners, and help guide PhD students. Applicants are expected to have a strong background in zebrafish embryology, live imaging, and developmental biology.
What you'll do
- Lead an independent research project investigating endoderm and mesoderm progenitor specification in zebrafish embryos.
- Examine the mechanisms of Erk mitotic erasure and its role in cell fate switching and cellular processes.
- Perform technical experiments utilizing zebrafish embryology, live imaging, and advanced image analysis.
- Contribute to collaborative projects within the laboratory and with external research partners.
- Guide and mentor PhD students in their research activities.
- Present research findings at scientific meetings and author publications in peer-reviewed journals.
Requirements
Degree required: PhD in a relevant biological science, ideally in developmental biology
Language: English
Instruction: English
Publications: Track record of writing papers as evidenced by publications or submitted manuscripts in refereed journals
- Good knowledge and experience of working with zebrafish as a developmental system
- Technical expertise in zebrafish embryology, live imaging, and image analysis
- Track record of writing papers as evidenced by publications or submitted manuscripts in referred journals
- Strong evidence of data presentation at scientific meetings
- Strong organisational skills and thorough record-keeping
- Ability to work independently and collaboratively in a team
- Applicants must meet the essential criteria listed within the role profile to have their application reviewed
- Eligible for visa sponsorship to work in the UK
Funding & terms
How to apply
Deadline: 2026-09-30 · open until filled
Interested candidates must review the full job description and submit their application through the official recruitment channel before the closing date. Ensure that all essential criteria outlined in the role profile are met prior to applying.
- CV
- Publications list or submitted manuscripts
Contact
Caroline Hill· Head of Developmental Signalling Laboratory
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