PhD Studentship in Healthy Ageing and Proteostasis Pathways
Explore how stress response activation influences extracellular matrix function to promote healthy ageing.
Best for:Best for enthusiastic biology graduates with a strong interest in genetics, ageing, and cellular stress mechanisms.
Overview
This four-year PhD studentship at the University of East Anglia investigates the intersection between cellular stress responses, extracellular matrix dynamics, and healthy ageing. Working within the Norwich Research Park Biosciences Doctoral Training Partnership, the successful candidate will use Caenorhabditis elegans models alongside advanced molecular and imaging techniques. The project aims to uncover how proteostasis pathways affect extracellular matrix structure and healthspan. Applicants will receive comprehensive training in multidisciplinary biological sciences and benefit from active engagement in scientific communication and research networks.
What you'll do
- Design and execute experimental studies investigating extracellular matrix composition and structure during ageing
- Utilize transcriptomic and proteomic approaches to analyse molecular changes in model organisms
- Apply advanced imaging methods such as confocal and transmission electron microscopy
- Perform genetic approaches combined with physiological and survival assays
- Contribute to scientific writing, presentation of findings, and active participation in lab meetings and journal clubs
Requirements
Degree required: BSc or equivalent in a relevant biological or biomedical science field
Degree offered: PhD
Language: English
Instruction: English
- Strong foundational knowledge in ageing biology and genetics
- Demonstrated enthusiasm and motivation for academic research
- Ability to design and conduct experimental biological assays
- Strong communication and analytical skills
- Eligible for admission under the Norwich Research Park Biosciences Doctoral Training Partnership criteria
Funding & terms
How to apply
Deadline: 2026-11-30
Interested applicants should prepare their application materials and submit them through the official University of East Anglia postgraduate research application portal. Ensure all required academic transcripts and supporting documents are attached prior to the deadline.
- CV
- Academic transcripts
- Cover letter
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