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Biological Sciences● OpenPreview

Doctoral Researcher in Protein Synthesis

Join a newly established lab at the University of Helsinki to investigate the mechanisms of protein synthesis and discover novel inhibitors.

Best for:Best for ambitious life science graduates with a background in biochemistry or molecular biology seeking rigorous multidisciplinary training in structural and chemical biology.

University of Helsinki · Helsinki, Finland · R1 · First-stage researcher
More professors at University of Helsinki
protein synthesisstructural biologycryo-electron microscopychemical biologydrug discovery
Deadline
Nov 13, 2026
30 days
Funding
Salaried
€2.5k–€2.7k/mo
Start date
January 2027
Fixed-term
Location
Helsinki
Finland

Overview

The University of Helsinki invites applications for a fully funded Doctoral Researcher position within the Faculty of Biological and Environmental Sciences. Working on the project 'Inhibiting Protein Synthesis – Old, New, Borrowed, Blue' funded by the Research Council of Finland, the successful candidate will conduct interdisciplinary research combining cellular and chemical biology, cell-free protein synthesis, and cryoEM. Under the supervision of Dr. Sarah O’Keefe and co-supervision of Brendan Battersby, the researcher will complete an article-based PhD thesis and 30 ECTS credits of doctoral studies. The appointee will benefit from close mentorship, international mobility, and access to state-of-the-art research infrastructures.

PhDdoctoral researcherprotein translationribosomecryoEMbiochemistrymolecular biologyUniversity of Helsinki

What you'll do

  • Perform cellular and molecular biology experiments to study the mechanisms of protein synthesis and translation.
  • Utilize advanced techniques such as cell-free protein synthesis, gene editing, and high-throughput screening.
  • Prepare samples and collaborate closely with local units for cryo-electron microscopy analysis.
  • Complete 30 ECTS credits of required coursework and write an article-based doctoral thesis.
  • Participate in international conferences and undertake short-term research visits to partner institutions such as the University of Leeds.
  • Contribute to scientific writing, project management, and collaborative tasks within an interdisciplinary research team.

Requirements

Degree required: Master’s degree in biology, biological sciences, biochemistry, pharmacy, or a related field

Degree offered: PhD

Language: English; excellent written and spoken proficiency

Instruction: English

Publications: Any publications or manuscripts in preparation should be listed in the CV if available.

Required skills
  • Ambition, collegiality, and motivation to pursue multidisciplinary scientific research
  • Ability to work independently, solve problems, and master new technical skills
  • Strong collaborative teamwork skills suited for an international research environment
  • Excellent written and spoken communication skills in English
Nice to have
Prior research experience in an industry setting or a research-intensive academic laboratoryFamiliarity with the field of protein synthesis and its underlying mechanismsBackground in medicinal chemistry with a demonstrated commitment to switching fieldsPrior exposure to molecular biology, cell culture, or protein expression techniques
Eligibility
  • Must hold or be due to complete a relevant Master’s degree prior to the start date
  • Must reside in Finland while employed by the University of Helsinki
  • Must secure the right to pursue a doctoral degree at the University of Helsinki within the six-month probationary period

Funding & terms

Type
Salaried
Amount
€2.5k–€2.7k/mo
Duration
44 months
Programme
Inhibiting Protein Synthesis – Old, New, Borrowed, Blue
Research Council of Finland

How to apply

Deadline: 2026-11-13 (Europe/Helsinki)

Prepare all required application documents combined into a single PDF file named using the format 'lastname_firstname'. Submit your application through the University of Helsinki electronic recruitment system using the 'Apply now' link before the deadline.

Documents required
  • Cover letter
  • CV
  • Master’s diploma
  • Transcript of records
  • 3 reference letters
  • Succinct answers to specific project-related questions
↗Apply on site

Contact

Sarah O’Keefe· Principal Investigator

sarah.okeefe@helsinki.fi

SO
Prof.
Sarah O’Keefe
Faculty of Biological and Environmental Sciences
Lab
O’Keefe Lab
University of Helsinki
Inhibiting Protein Synthesis – Old, New, Borrowed, BlueFinland
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