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Biomedical Sciences● Open⏰ 6 days left×18 positionsPreview

PhD Studentship: Decoding Sex Chromosome Effects in the Human Brain

Investigate how X and Y chromosomes shape gene expression and brain health in neuropsychiatric diseases.

Best for:Best for bioinformatics and computational biology students interested in multi-omic data analysis and neurogenetics.

University of Exeter · South West England, United Kingdom · R1 · First-stage researcher
More professors at University of Exeter
Sex ChromosomesBioinformaticsSingle-Cell GenomicsNeurodegenerationEpigenetics
Deadline
Oct 21, 2026
6 days
Funding
Salaried
£21.8k/yr
Start date
October 2027
Full-time
Location
South West England
United Kingdom

Overview

The GW4 BioMed3 Doctoral Landscape Programme offers a four-year PhD studentship at the University of Exeter focused on decoding sex chromosome effects in the human brain. The research utilizes cutting-edge multi-omic and single-cell datasets to explore how X and Y chromosomes drive molecular differences in both healthy aging and neuropsychiatric disorders. The successful candidate will join a dynamic bioinformatics research team to uncover the biological foundations of sex differences in brain health. Applicants are expected to hold an appropriate academic degree and engage enthusiastically with large-scale genomic and transcriptomic datasets.

PhDStudentshipBioinformaticsGenomicsBrain DisordersMulti-omics

What you'll do

  • Analyze cutting-edge multi-omic and single-cell datasets to study sex chromosome gene expression.
  • Investigate molecular differences driven by X and Y chromosomes at the cellular level.
  • Examine sex-specific differences in brains affected by neuropsychiatric and neurodegenerative diseases.
  • Collaborate with international research teams and internal project partners.
  • Contribute to scientific publications and present research findings at academic conferences.

Requirements

Degree required: BSc or MSc in a relevant scientific discipline such as Bioinformatics, Computer Science, Biological Sciences, or related field

Degree offered: PhD

Language: English

Instruction: English

Required skills
  • Background in bioinformatics, computational biology, or biomedical sciences
  • Experience with data analysis or programming for biological datasets
  • Interest in genomics, transcriptomics, or neurogenetics
Nice to have
Experience working with single-cell or multi-omic datasetsFamiliarity with neurodegenerative or neuropsychiatric disease research
Eligibility
  • Open to UK and International students

Funding & terms

Type
Salaried
Amount
£21.8k/yr
Duration
4 years
Programme
GW4 BioMed3 MRC Doctoral Landscape Programme
Medical Research Council (MRC)

How to apply

Deadline: 2026-10-21

Interested applicants should review the project details and submit their applications through the official GW4 BioMed3 application portal. Ensure all required academic transcripts and supporting documents are provided prior to the deadline.

Documents required
  • CV
  • Cover letter
  • Academic transcripts
  • Reference letters
↗Apply via form

Contact

Lab
GW4 BioMed3 Doctoral Landscape Programme
University of Exeter
GW4 BioMed3 MRC Doctoral Landscape ProgrammeUnited Kingdom
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