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Computational Biology and Protein Engineering● OpenPostdocPreview

Postdoc in AI-driven design of environment-responsive antibodies

Develop deep learning and generative models for environment-responsive antibodies and nanobodies at DTU Bioengineering.

Best for:Best for machine learning researchers and computational biologists with a strong background in deep learning, generative modeling, and protein science.

Technical University of Denmark (DTU) · Lyngby, Denmark · R2 · Recognised researcher
More professors at Technical University of Denmark (DTU)
Machine LearningProtein EngineeringGenerative ModelsAntibody DiscoveryComputational Biology
This is a postdoc position — not a PhD studentship.
Deadline
Nov 3, 2026
17 days
Funding
Salaried
Competitive salary based on the collective agreement with the Danish Confederation of Professional Associations
Start date
2027-02-01
Full-time
Location
Lyngby
Denmark

Overview

The Technical University of Denmark (DTU) is inviting applications for a four-year postdoctoral position in the Antibody Technologies Group at DTU Bioengineering. Working on the Villum Foundation-funded project PROTÆCT, the successful candidate will focus on the computational design of antibodies and nanobodies with condition-dependent activity. The role bridges machine learning and protein engineering, involving close collaboration with wet-lab scientists and international partners. The applicant is expected to take project ownership, publish impactful research, and mentor students.

PostdocArtificial IntelligenceDeep LearningAntibody TechnologiesProtein DesignPyTorchGenerative AI

What you'll do

  • Design and implement advanced deep learning architectures for biochemical environment-sensing binding proteins
  • Develop and optimize generative models dedicated to de novo protein binder design
  • Collaborate closely with wet-lab researchers to express, test, and validate computational designs
  • Publish scientific findings in high-impact international journals and contribute to grant proposals
  • Manage scientific projects and provide co-leadership within the research team
  • Mentor and train PhD, MSc, and BSc students

Requirements

Degree required: PhD in Computer Science, Machine Learning, Artificial Intelligence, Computational Biology, or a closely related field

Language: English; excellent written and spoken proficiency

Instruction: English

Publications: Strong publication record in relevant AI/ML or interdisciplinary journals

Required skills
  • Strong theoretical and practical experience in deep learning
  • Hands-on experience in developing generative models
  • High proficiency in Python, PyTorch, and/or JAX
  • Experience training large-scale neural networks on high-performance computing or GPU clusters
  • Experience with representation learning and sequence or structural modeling
  • Strong publication record in relevant AI/ML or interdisciplinary venues
  • Demonstrated ability to work independently, manage projects, and mentor students
Nice to have
Experience with protein language models or antibody-specific language modelsExperience with structure prediction frameworks, geometric deep learning, or graph neural networksFamiliarity with computational antibody discovery or molecular modeling
Eligibility
  • Must hold a PhD degree or equivalent by the start of the appointment

Funding & terms

Type
Salaried
Amount
Competitive salary based on the collective agreement with the Danish Confederation of Professional Associations
Duration
4 years
Programme
PROTÆCT
Villum Foundation

How to apply

Deadline: 2026-11-03 (Europe/Copenhagen)

Candidates must submit a complete online application through the official DTU recruitment portal by the specified deadline. All application materials must be combined into a single PDF file written in English, including a cover letter, CV, academic diplomas, and a publication list.

Documents required
  • Cover letter
  • CV
  • Academic Diplomas
  • List of publications
↗Apply on site

Contact

Andreas Hougaard Laustsen-Kiel· Professor & Head of Section

ahola@bio.dtu.dk

http://www.bioengineering.dtu.dk/

AH
Prof.
Andreas Hougaard Laustsen-Kiel
Department of Biotechnology and Biomedicine
Lab
Antibody Technologies Group
Technical University of Denmark (DTU)
PROTÆCTDenmark
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