Postdoctoral Research Associate in Fungal Pathogen Genetics and Engineering Biology
Develop an AI-driven antifungal drug discovery platform for *Candida auris* using CRISPR screens and single-cell analysis.
Best for:Best for postdoctoral researchers with a PhD in bioengineering, genetics, or synthetic biology, strong hands-on experience in CRISPR, NGS, and bioinformatics, and a passion for translational fungal pathogen research.
Overview
This postdoctoral position at Imperial College London’s Department of Bioengineering offers a collaborative opportunity to advance antifungal drug discovery for the critical pathogen *Candida auris*. Under the joint supervision of Dr. Sonja Billerbeck and Prof. Rodrigo Ledesma-Amaro, the successful candidate will lead CRISPR-based gene prediction, single-cell sequencing, and tool development within a Wellcome Trust-funded consortium. The interdisciplinary role spans bioinformatics, yeast genetics, and molecular biology, with a focus on scalable bioreactor assays and next-generation sequencing. Applicants should demonstrate expertise in genetic engineering, data analysis, and collaborative research while contributing to high-impact publications and conference presentations. The position emphasizes innovation, interdisciplinary teamwork, and mentorship of undergraduate/postgraduate students.
What you'll do
- Lead CRISPR-based gene prediction and verification through large-scale screens for *Candida auris*.
- Develop and optimize single-cell sequencing assays to study population heterogeneity in fungal pathogens.
- Design and execute competitive growth assays in small-scale bioreactors for antifungal drug testing.
- Collaborate with a multi-PI consortium to integrate findings into an AI-driven antifungal drug discovery platform.
- Present research at international conferences and publish findings in peer-reviewed journals.
- Supervise undergraduate and postgraduate research students in laboratory and analytical techniques.
- Ensure data validity and reliability through rigorous methodological design and statistical analysis.
Requirements
Degree required: PhD in bioengineering, yeast genetics, synthetic biology, natural sciences, biological sciences, or a closely related discipline, or equivalent research/industrial experience.
Language: English (proficiency sufficient for academic research and collaboration)
Instruction: English
Publications: Publication(s) in peer-reviewed journals and project reports to the research sponsor.
- Practical experience in molecular biology (e.g., cloning, genome engineering).
- Proficiency in bioinformatics and large-scale data analysis, including NGS.
- Experience with microbiological culturing and assay/tool development.
- Knowledge of research methods and statistical procedures.
- Publication record in relevant peer-reviewed journals.
- Experience collaborating with sponsors and academic partners.
- No explicit nationality or residency restrictions mentioned.
- No age or prior experience caps specified.
Funding & terms
How to apply
Deadline: 2026-11-01
Applicants must submit their CV, cover letter, and research statement through Imperial College London’s job portal. Additional documents may include academic transcripts and contact details for three referees. Ensure all materials are tailored to highlight relevant research experience and alignment with the project goals.
- CV
- Cover letter
- Research statement
- Academic transcripts (if applicable)
- Three reference letters
Contact
Dr. Sonja Billerbeck / Prof. Rodrigo Ledesma-Amaro· Supervisors
Create a free profile to unlock your personal match score, the full requirements, funding details and how to apply — in English or Persian.