Optical Intradermal Sensing via Instrumented Microneedles
Develop advanced optical microneedles for continuous, minimally invasive intradermal monitoring of cortisol.
Best for:Best for graduate engineers with a strong background in optics, biophotonics, or instrumentation seeking a PhD in health technologies.
Overview
This doctoral project, hosted at Université Grenoble Alpes and the CEA Leti laboratory, focuses on developing an innovative measurement device for continuous, minimally invasive cortisol monitoring. The research candidate will design and size optical microneedles functionalized with fluorescent aptamers, build experimental characterization systems, and test performance in representative environments. Additionally, the researcher will create a comprehensive data processing and analysis methodology to correlate optical signals with precise cortisol concentrations. The successful applicant will work alongside leading scientists in optics and health technologies to advance in situ health monitoring.
What you'll do
- Design and dimension optical microneedles dedicated to continuous cortisol detection
- Set up experimental testbeds to characterize fabricated optical microneedles
- Evaluate sensor performance and reliability in representative operating environments
- Develop data processing and analysis pipelines to translate optical signals into quantitative cortisol measurements
- Collaborate with multidisciplinary teams at CEA Leti to integrate emission and detection technologies
Requirements
Degree required: Master's degree in Optics, Physics, Instrumentation, Biomedical Engineering, or equivalent
Degree offered: PhD
Language: English; French: None required
Instruction: English / French
- Strong background in optical instrumentation and measurement systems
- Experience with experimental setup design and sensor characterization
- Proficiency in data analysis and processing methodologies
- Ability to work in a collaborative, multidisciplinary research laboratory
Funding & terms
How to apply
Deadline: 2026-10-31
Interested candidates should review the application requirements on the official portal and submit their application materials directly through the designated submission system. Ensure all required documentation is prepared and submitted before the deadline.
- CV
- Cover letter
- Academic transcripts
Contact
Guillaume Blanquer· Supervisor
33 (0)4 38 78 36 98
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