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Biological sciences● Open⏰ 0 days leftPreview

PhD Position: High Resolution Fluorescence Imaging of Protein Plasticity

Explore protein dynamics and microphase separation using quantitative single-molecule and super-resolution imaging.

Best for:Best for quantitative scientists, physicists, and biophysicists with a strong interest in applying advanced imaging and physical techniques to molecular biology.

International PhD Programme (IPP) Mainz · Mainz, Germany · R1 · First-stage researcher
More professors at International PhD Programme (IPP) Mainz
intrinsically disordered proteinssingle-molecule imagingsuper-resolution microscopymicrophase separationprotein dynamics
Deadline
Oct 15, 2026
0 days
Funding
Salaried
Fully funded positions with financing until the completion of your thesis
Start date
2027-02-01
Full-time
Location
Mainz
Germany

Overview

The International PhD Programme (IPP) Mainz invites applications for a fully funded doctoral position within the Institute of Molecular Biology. Working in Edward Lemke's research group, the successful candidate will investigate intrinsically disordered proteins and protein plasticity using advanced single-molecule, microfluidics, and super-resolution techniques. The project focuses on understanding associative mechanisms and sub-resolution structures within the context of microphase separation and transcriptional regulation. Applicants from quantitative backgrounds such as physics, biophysics, and computational chemistry, as well as motivated life scientists, are encouraged to apply.

PhDfluorescence imagingbiophysicsquantitative biologysuper-resolutionmolecular biologyprotein plasticity

What you'll do

  • Develop and apply quantitative single-molecule and super-resolution fluorescence imaging technologies to study protein dynamics.
  • Investigate sub-resolution structures and associative mechanisms related to microphase separation and transcriptional regulation.
  • Collaborate within an interdisciplinary team combining chemical biology, synthetic biology, and microfluidics.
  • Participate in advanced scientific training programmes, professional development workshops, and core facility activities.
  • Present research findings at internal meetings and international conferences, and contribute to scientific publications.

Requirements

Degree required: Master Degree or equivalent

Degree offered: PhD

Language: English; good command required

Instruction: English

Required skills
  • Master degree or equivalent in physics, biophysics, polymer science, physical chemistry, biology, biochemistry, or a related discipline
  • Strong motivation and high interest in interdisciplinary quantitative biosciences
  • Good command of the English language
Nice to have
Background in physical sciences or computational methodsPrior experience in experimental biosciences or advanced microscopy

Funding & terms

Type
Salaried
Amount
Fully funded positions with financing until the completion of your thesis
Duration
Duration of thesis
Programme
International PhD Programme (IPP) Mainz
International PhD Programme (IPP) Mainz

How to apply

Deadline: 2026-10-15 (Europe/Berlin)

Interested candidates must apply through the online application platform provided by the International PhD Programme. Select Lemke as your group preference in the application form and ensure all required documents, including reference letters, are submitted by the deadline.

Documents required
  • CV
  • 2 letters of reference
↗Apply via form

Contact

EL
Prof.
Edward Lemke
Institute of Molecular Biology
Lab
Edward Lemke Research Group
International PhD Programme (IPP) Mainz
Germany
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