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Ophthalmic Epidemiology● OpenOpen until filledPreview

PhD Candidate in Ophthalmic Epidemiology

Explore the genetic, molecular, and environmental factors driving age-related macular degeneration using multi-omics and eye imaging data.

Best for:Best for early-career researchers with a strong background in epidemiology, bioinformatics, or biomedical sciences, passionate about quantitative analysis and multi-omics data integration.

German Center for Neurodegenerative Diseases (DZNE) · Bonn, Germany · R1 · First-stage researcher
More professors at German Center for Neurodegenerative Diseases (DZNE)
age-related macular degenerationmulti-omics data integrationeye imaging data analysisepidemiological researchpopulation-based cohort studiesgenetic and molecular factors in aging
Deadline
Until filled
rolling
Funding
Salaried
Not specified
Start date
15.10.2026
Full-time
Location
Bonn
Germany

Overview

This PhD position at the German Center for Neurodegenerative Diseases (DZNE) focuses on investigating the relationship between aging and age-related macular degeneration (AMD) through integrative analyses of multi-omics and eye imaging data. The project is embedded within the Rhineland Study, a large-scale population-based cohort study involving over 14,000 participants with extensive longitudinal data. The successful candidate will conduct cutting-edge research under the supervision of Dr. Dr. Petra Larsen, contributing to data collection, statistical analyses, manuscript preparation, and conference presentations. The role emphasizes interdisciplinary collaboration, independent research development, and participation in an international team.

ophthalmic epidemiologymulti-omics analysisage-related macular degenerationepigenomicstranscriptomicsmachine learning in epidemiologypopulation health researchlongitudinal cohort studies

What you'll do

  • Perform integrative analyses combining multi-omics data (e.g., genomics, transcriptomics, metabolomics) with eye imaging data to study age-related macular degeneration.
  • Contribute to ophthalmic data collection, processing, and coordination within the Rhineland Study cohort.
  • Conduct statistical analyses and prepare manuscripts for publication in peer-reviewed journals.
  • Present research findings at national and international conferences.
  • Participate in project-related meetings, documentation, and progress reporting.
  • Develop independent research ideas and contribute to ongoing projects within the research team.

Requirements

Degree required: Master’s degree (or equivalent) in epidemiology, bioinformatics, medicine, biomedical sciences, or a related discipline

Degree offered: PhD

Language: English; proficiency required for research and communication

Instruction: English

Required skills
  • Strong proficiency in written and spoken English
  • Statistical knowledge and experience with programming in R
  • Experience with epidemiological research or large-scale observational studies
  • Strong analytical skills and independent critical thinking
  • Attention to detail in data processing and analysis
Nice to have
Experience with machine learning methods for pattern recognition and predictive modelingFamiliarity with omics and eye imaging data analysisProficiency in written and spoken German
Eligibility
  • No specific nationality or residency restrictions mentioned
  • No age limits or prior experience caps specified

Funding & terms

Type
Salaried
Amount
Not specified
Duration
3 years, extension possible
Programme
German Center for Neurodegenerative Diseases (DZNE)
German Center for Neurodegenerative Diseases (DZNE)

How to apply

Applicants must submit a single PDF file containing a cover letter, CV, and transcripts. The cover letter should describe motivation, alignment with the research group’s work, and highlight relevant projects, publications, or collaborations. Authentic applications are encouraged, and AI-generated cover letters are discouraged.

Documents required
  • Cover letter
  • CV
  • Transcripts
↗Apply on site

Contact

Petra Larsen· Scientific Lead, Ophthalmic Epidemiology Team

petra.larsen@dzne.de

PL
Prof.
Petra Larsen
Ophthalmic Epidemiology
Lab
Ophthalmic Epidemiology Research Team
German Center for Neurodegenerative Diseases (DZNE)
Germany
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