PhD candidate in Systems Medicine
Join an interdisciplinary team investigating the impact of environmental pollutants on the immune system.
Best for:Best for candidates with a background in molecular biology or bioinformatics and a strong interest in immunaging and omics technologies.
Overview
The German Center for Neurodegenerative Diseases (DZNE) in Bonn is seeking a motivated PhD candidate to join the Systems Medicine research group. This position focuses on molecular and translational immunaging, specifically examining how chronic exposure to per- and polyfluoroalkyl substances (PFAS) affects immune function. The successful candidate will utilize advanced omics technologies, organoid systems, and animal models to uncover underlying molecular mechanisms. You will work in a highly collaborative, international environment alongside experts in immunology, data science, and epidemiology.
What you'll do
- Design and execute single-cell multi-omics and high-dimensional cytometry experiments.
- Develop and maintain organoid and animal model systems for experimental research.
- Perform comprehensive data analysis using modern computational pipelines.
- Investigate the impact of PFAS exposure on immune system pathways.
- Identify molecular pathways and potential intervention strategies for immune dysfunction.
- Collaborate with interdisciplinary experts in data science, immunology, and epidemiology.
- Utilize established genomics, bioinformatics, and high-performance computing facilities.
Requirements
Degree required: Master or equivalent in molecular biology, immunology, bioinformatics, systems biology, or related fields.
Degree offered: PhD
Language: Very good English proficiency.
Instruction: English
- Strong research background in immunology, cell biology, and genomics or transcriptomics.
- Strong interest in omics technologies and computational analysis.
- Very good English proficiency.
- Ability to work independently and as part of an international team.
- Excellent communication and collaborative skills.
Funding & terms
How to apply
Deadline: 2026-10-06
Interested candidates should submit their application through the official DZNE job portal. Ensure all required documents are prepared and uploaded according to the portal instructions.
- CV
- Cover letter
- Academic transcripts
Contact
Lorenzo Bonaguro· Principal Investigator
+49 228 43302 147
https://www.dzne.de/en/research/research-areas/systems-medicine/
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