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Chemical Engineering● OpenPreview

PhD Position in Characterization and Modelling of Particle Flow Properties

Develop advanced 3D numerical models to simulate pharmaceutical manufacturing processes like hot-melt extrusion and twin-screw melt granulation.

Best for:Best for engineering graduates with a strong background in chemical, mechanical, or materials engineering and an interest in multiphase flow simulations.

VSCHT Praha · Prague, Czech Republic · R1 · First-stage researcher
More professors at VSCHT Praha
Particle flow modellingDiscrete element methodComputational fluid dynamicsHot-melt extrusionTwin-screw melt granulationMultiscale simulation
Deadline
Dec 13, 2026
60 days
Funding
—
Temporary
Start date
2026-10-01
Full-time
Location
Prague
Czech Republic

Overview

The Department of Chemical Engineering at the University of Chemistry and Technology Prague is offering a PhD position focused on characterizing and modelling particle flow properties. The project bridges experimental work with discrete element method (DEM) and computational fluid dynamics (CFD) simulations to optimize pharmaceutical manufacturing processes such as hot-melt extrusion and twin-screw melt granulation. The successful candidate will integrate particle-level surface properties and multiscale modelling approaches to evaluate how operating parameters influence final material characteristics. The research involves collaborating closely with experimental PhD students to build a comprehensive 3D process model for pilot-scale equipment scale-up.

DEM simulationCFDpowder flowpharmaceutical engineeringmultiscale modellingparticle adhesionrheological properties

What you'll do

  • Perform particle-level surface property characterization and integrate findings into numerical simulations
  • Develop and execute discrete element method (DEM) simulations to model powder flow during extrusion and granulation
  • Couple DEM simulations of extruders with computational fluid dynamics (CFD) models of molten material
  • Adjust particle contact mechanics and adhesion models based on varying temperature and processing conditions
  • Collaborate with experimental researchers to combine simulation outcomes with laboratory data
  • Construct a comprehensive 3D process model to support scale-up to pilot-scale manufacturing equipment

Requirements

Degree required: Master Degree or equivalent in Chemical Engineering, Mechanical Engineering, Materials Science, or a related field

Degree offered: PhD

Language: English; good working proficiency required

Instruction: English

Required skills
  • Solid foundation in chemical, mechanical, or materials engineering principles
  • Familiarity with numerical simulation techniques or particle-based modelling
  • Strong analytical and problem-solving skills for complex multiphase systems
  • Ability to work collaboratively within an interdisciplinary research team
Nice to have
Prior experience with Discrete Element Method (DEM) software or Computational Fluid Dynamics (CFD)Knowledge of rheology, powder mechanics, or pharmaceutical unit operationsProgramming experience in Python, C++, or similar languages for scientific computing
Eligibility
  • Hold a recognized Master's degree or equivalent qualification prior to appointment

Funding & terms

Type
Unknown
Amount
—
Duration
Temporary
Programme
Not funded by a EU programme
University of Chemistry and Technology Prague

How to apply

Deadline: 2026-12-13 (Europe/Prague)

Interested applicants should submit their application materials directly via email to the contact address provided. Ensure the subject line references the specific project title.

Documents required
  • CV
  • Master Degree certificate
  • Transcripts
✉Apply by email

Contact

MS
Prof.
Miroslav Soos
Department of Chemical Engineering
Lab
BEAM Lab
VSCHT Praha
Not funded by a EU programmeCzech Republic
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