PhD Position in Radiology and Brain Clearance Mechanisms
Investigate the brain's waste clearance system and its link to dementia using innovative MRI and wearable sensors.
Best for:Best for master's graduates with an interdisciplinary background in engineering and physiology or neurology, and strong Dutch language skills.
Overview
This PhD position investigates the brain clearance system to understand how cerebrospinal fluid removes waste products and how disruptions contribute to dementia. The successful candidate will conduct clinical research involving older adults with memory issues and patients with hypertension using advanced MRI techniques and the wearable 'glymphometer' device. Responsibilities include designing study protocols, recruiting and guiding participants, acquiring imaging data, and analyzing results in accordance with international standards. The project is a collaborative effort between the Leiden University Medical Center and Radboud University Medical Center, providing a multidisciplinary research environment.
What you'll do
- Set up and execute clinical research studies, including participant recruitment and guidance.
- Perform MRI scans and measurements using the wearable glymphometer device.
- Process, analyze, and interpret research data adhering to data quality and ICH-GCP guidelines.
- Present research findings at national and international scientific conferences.
Requirements
Degree required: Completed university master's degree (wo-opleiding) at the intersection of engineering and physiology or neurology
Degree offered: PhD
Language: Very good command of the Dutch language (C1 level), both spoken and written
Instruction: Dutch, English
- Interdisciplinary collaboration across technical and medical domains
- Clear communication and active participation in study planning
- Meticulous attention to detail in data administration and record keeping
- Curiosity regarding new techniques and complex scientific questions
- Open to internal and external candidates
Funding & terms
How to apply
Deadline: 2026-11-05
Submit your application through the online portal by following the application link provided. Ensure all required materials are uploaded before the deadline.
- CV
- Cover letter
Contact
Thijs van Osch· Professor
071 526 36 78
https://www.lumc.nl/en/afdelingen/radiologie/c.j.gorter-mri-center
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