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Biophysics● Open★ EU-FUNDEDPreview

PhD Position in Single-Molecule Biophysics

Join an interdisciplinary project using single-molecule techniques and computational tools to advance therapeutic molecular research.

Best for:Best for candidates with an MSc in physics, biophysics, or computational biology and strong Python programming skills.

Delft University of Technology (TU Delft) · Delft, Netherlands · R1 · First-stage researcher
More professors at Delft University of Technology (TU Delft)
Single-molecule biophysicsMolecular interactionsComputational biologyProtein-ligand interactionsMachine learning validationFluorescence microscopy
Deadline
Nov 1, 2026
18 days
Funding
Salaried
€3.1k–€3.9k/mo
Start date
flexible
Full-time
Location
Delft
Netherlands

Overview

Delft University of Technology is seeking a motivated PhD candidate to join the Faculty of Applied Sciences for a project focused on molecular mechanisms in biological systems. The research involves applying single-molecule fluorescence and biochemistry alongside computational methods to study protein-ligand and protein-peptide interactions. You will work in an international, interdisciplinary environment to generate multiplexing data and validate machine learning predictions. This position is part of a Marie Skłodowska-Curie Doctoral Network, offering the opportunity to collaborate with international partners on therapeutic applications. The successful candidate will contribute to both fundamental and medical sciences while developing their research and transferable skills.

PhDBiophysicsSingle-moleculeComputational biologyMarie CurieTU DelftMolecular biology

What you'll do

  • Apply single-molecule fluorescence and biochemical techniques to study molecular mechanisms.
  • Develop and utilize computational methods for data analysis.
  • Generate high-throughput single-molecule multiplexing data.
  • Validate machine learning predictions using experimental datasets.
  • Collaborate with international partners on therapeutic research applications.
  • Participate in the TU Delft Graduate School doctoral education programme.
  • Communicate research findings through scientific articles and a final thesis.

Requirements

Degree required: MSc degree (or nearing completion) in physics, biophysics, computational biology, or a related field.

Degree offered: PhD

Language: English; proficiency required for scientific writing and communication.

Instruction: English

Required skills
  • Strong programming skills in Python.
  • Experience in data analysis and computational methods.
  • Familiarity with molecular biology techniques.
  • Excellent written and spoken English proficiency.
Nice to have
Experience in an interdisciplinary research environment.Previous experience with single-molecule fluorescence microscopy.
Eligibility
  • Must satisfy the MSCA mobility rule: must not have lived or worked/studied in the Netherlands for more than 12 months in the 36 months prior to recruitment.

Funding & terms

Type
Salaried
Amount
€3.1k–€3.9k/mo
Duration
4 years
Programme
Marie Skłodowska-Curie Actions Doctoral Network
EU-FUNDEDEuropean Commission

How to apply

Deadline: 2026-11-01

Interested candidates should email Chirlmin Joo for an inquiry before applying. Applications must be submitted via the official portal by the deadline, including a CV and a motivational letter.

Documents required
  • CV
  • Motivational letter
↗Apply on site

Contact

CJ
Prof.
Chirlmin Joo
Faculty of Applied Sciences
Lab
Faculty of Applied Sciences
Delft University of Technology (TU Delft)
Marie Skłodowska-Curie Actions Doctoral NetworkNetherlands
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