Postdoctoral Research Scientist - Epitranscriptomics
Lead cutting-edge research investigating pseudouridine and cancer biology within the Target Discovery Institute at Oxford.
Best for:Best for molecular biologists and biochemists with strong expertise in epitranscriptomics, RNA modifications, and CRISPR technologies.
Overview
The University of Oxford is seeking a Postdoctoral Research Scientist in Epitranscriptomics to join Dr Chunxiao Song's research group at the Target Discovery Institute. The position focuses on developing innovative technologies to map DNA and RNA modifications, specifically investigating the roles of pseudouridine and pseudouridine synthases in cancer. The successful candidate will manage and drive research projects, develop experimental protocols, analyze complex datasets, and contribute to scientific publications and funding proposals. This is a full-time, fixed-term opportunity for 12 months, funded by Ludwig Cancer Research.
What you'll do
- Manage and independently drive research projects focused on pseudouridine and pseudouridine synthases in cancer.
- Adapt, develop, and optimize experimental techniques and laboratory protocols.
- Perform genetic and molecular assays using CRISPR-Cas9 knockout cell lines.
- Analyze and interpret complex scientific data concerning DNA and RNA modifications.
- Prepare scientific reports, journal articles, and presentations for internal and external stakeholders.
- Contribute novel ideas for new research directions and future funding opportunities.
- Supervise, train, and provide technical guidance to junior laboratory members.
- Collaborate actively with interdisciplinary colleagues and partner institutions.
Requirements
Degree required: PhD or DPhil in Molecular Biology, Biochemistry, Biology, Chemistry, or a related scientific discipline
Language: English
Instruction: English
Publications: Prior peer-reviewed publications are required, with first-author publications in relevant fields considered advantageous.
- Extensive knowledge of epigenetics, epitranscriptomics, and RNA pseudouridine
- Demonstrated laboratory skills in molecular biology, biochemistry, and cell biology
- Hands-on experience with CRISPR-Cas9 knockout cell lines
- Competence in bioinformatic analysis of DNA and RNA modifications, including small RNAs
- Experience in recombinant protein expression and purification
- Proven ability to conduct independent research and supervise laboratory members
Funding & terms
How to apply
Deadline: 2026-11-26
Applicants must apply online through the University of Oxford recruitment portal by submitting a comprehensive CV and a supporting statement. The supporting statement must explicitly detail how the applicant meets each of the selection criteria using concrete examples from their background.
- CV
- Supporting statement
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