Doctoral Researcher in β-Catenin Ligands & Cell Differentiation
Join a dynamic research team focused on cell differentiation and Wnt signaling.
Best for:Best for candidates with a strong background in biochemistry and cell biology.
Overview
The University of Luxembourg is seeking a Doctoral Researcher to explore the role of β-catenin ligands in cell differentiation. This position involves developing biosensors to study intracellular interactions and the effects of peptidic ligands on Wnt/β-catenin signaling in C2C12 cells. The successful candidate will engage in hands-on experimental work and contribute to a multidisciplinary research environment. Applicants should be motivated to publish and participate in conferences.
What you'll do
- Assess the impact of Wnt signaling on C2C12 progenitor cells and their differentiation.
- Create specialized BRET biosensors to monitor protein interactions within the Wnt pathway.
- Examine how peptidic ligands influence Wnt/β-catenin signaling and differentiation.
- Conduct measurements of cellular differentiation and β-catenin localization.
- Develop BRET biosensors for tracking target engagement and molecular processes.
- Combine cellular data with ligand optimization efforts in the FlexCAT program.
Requirements
Degree required: MSc in Biochemistry, Developmental Biology, Biophysical Chemistry or a related field
Degree offered: PhD
Language: English; excellent proficiency required
Instruction: English
- Strong understanding of molecular biochemistry
- Experience with fluorescence microscopy and bioluminescence techniques
- Basic skills in cell culture and cellular differentiation models
- Excellent project management and communication abilities
- Must comply with MSCA mobility rule: no more than 12 months of residence in Luxembourg in the last 36 months
- Must qualify for doctoral admission
Funding & terms
How to apply
Deadline: 2026-11-30
Applications must be submitted exclusively through the FlexCAT Recruitment Portal. Follow the steps to select the project and complete your application online.
- CV
- Cover letter
- Transcripts
- Proof of language proficiency
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