Lead Scientist - Directing Cryo-Electron Microscopy and Tomography Center
Lead a state-of-the-art Cryo-EM/Cryo-ET facility supporting cutting-edge pediatric research.
Best for:Best for experienced structural biologists or biophysicists with extensive leadership experience in high-end cryo-EM facility management.
Overview
St. Jude Children's Research Hospital is seeking an experienced scientific leader to direct its Cryo-Electron Microscopy and Tomography Center. The successful candidate will oversee daily operations, manage a team of staff scientists, and advance high-throughput imaging workflows in collaboration with the Center of Excellence for Structural Cell Biology. This role involves strategic planning for instrumentation, user training, and providing expert support for structural biology projects across diverse pediatric research areas. The position offers a collaborative, well-resourced environment dedicated to translating scientific innovation into clinical outcomes.
What you'll do
- Provide scientific and operational leadership for the Cryo-EM/Cryo-ET Center in collaboration with faculty users.
- Supervise and mentor a team of staff scientists responsible for instrument operations and data processing.
- Oversee the scheduling, utilization, and performance of high-end cryo-EM instrumentation.
- Develop and implement training programs for users on sample preparation, microscope operation, and data collection.
- Collaborate with investigators to design imaging strategies for structural biology and cellular imaging projects.
- Drive the development and optimization of emerging cryo-EM/cryo-ET methodologies and automation workflows.
- Coordinate with vendors and service engineers to maintain optimal instrument performance and minimize downtime.
- Maintain standard operating procedures, safety documentation, and quality-control processes.
Requirements
Degree required: Bachelor's degree in a relevant scientific area
Language: English
Instruction: English
- Significant hands-on experience with Cryo-EM/Cryo-ET workflows
- Demonstrated expertise in operating high-end 200 and 300 kV TEM systems
- Strong leadership and team management experience
- Proven ability to work collaboratively in a multidisciplinary research environment
- Strong organizational and communication skills
- 12 years of relevant experience with a Bachelor's degree
- 10 years of relevant experience with a Master's degree
- 7 years of relevant experience with a PhD
Funding & terms
How to apply
Deadline: 2026-11-04
Interested candidates should submit their application through the official St. Jude careers portal. Please ensure all required documentation is uploaded to be considered for the position.
- CV
- Cover letter
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