Research Associate / Senior Research Associate in Neural Control of Cardioprotection

The University of Bristol is seeking a Research Associate or Senior Research Associate to join a research programme focused on the neural control of cardioprotection and cardiac microcirculation. The project investigates how metabolic and oxidative stressors affect cardiac microcirculation and how central brain circuits can be leveraged to promote angiogenesis following myocardial infarction. The successful candidate will employ a range of in vitro, ex vivo, and in vivo techniques, including viral vector-based circuit mapping and surgical models of heart failure. The appointment level will be determined based on the candidate's qualifications and experience, with the role initially funded for two years.

• Plan, execute, and analyze experiments using in vitro, ex vivo, and in vivo methodologies.
• Perform complex in vivo surgical procedures, including induction of myocardial infarction and stereotaxic viral vector injections.
• Design and implement viral vectors for neuronal circuit mapping.
• Conduct cell culture experiments using primary cells and human hPSC-derived models.
• Perform advanced in vivo imaging techniques such as echocardiography and laser Doppler/speckle imaging.
• Manage transgenic mouse colonies and contribute to methodology enhancement (Senior level).
• Prepare manuscripts, grant applications, and literature reviews for publication and dissemination.