Doctoral (PhD) Student Position in T-cell Biology in Rheumatic Diseases

Karolinska Institutet invites applications for a fully-funded four-year doctoral student position focusing on T-cell biology in rheumatic diseases. Working within the Rheumatology Division under the supervision of Associate Professor Karine Chemin and a team of co-supervisors, the successful candidate will investigate regulatory T cells and tissue-resident memory T cells in conditions such as rheumatoid arthritis and myositis. The role involves collecting and analyzing human clinical samples, employing advanced techniques such as full-spectrum flow cytometry and single-cell sorting, and collaborating closely with clinicians and international researchers. Candidates are expected to actively engage in coursework, scientific meetings, independent experimentation, and manuscript writing.

• Collect and process primary human clinical samples including synovial fluid, biopsies, and peripheral blood.
• Perform laboratory techniques including full-spectrum flow cytometry, single-cell sorting, immunofluorescence, and in vitro cell culture.
• Conduct bioinformatic analyses and manage experimental data using an electronic lab book.
• Plan and execute experiments independently under the guidance of experienced supervisors.
• Collaborate with clinical teams at the rheumatology clinic and international research partners.
• Present findings regularly at internal group meetings and international scientific conferences.
• Read relevant scientific literature and draft manuscripts for publication.
• Complete individual study plan requirements and relevant doctoral coursework.