PhD Monitor
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Computational Biology● OpenPostdocOpen until filledPreview

Postdoctoral Fellow in Computational Protein Design and Machine Learning

Join a dynamic team focused on innovative protein engineering.

Best for:Ideal for computational biologists with a strong background in protein design and machine learning.

University of Maryland Baltimore · Baltimore, United States · R2 · Recognised researcher
More professors at University of Maryland Baltimore
Computational Protein DesignMachine LearningStructural BioinformaticsMolecular Engineering
This is a postdoc position — not a PhD studentship.
Deadline
Until filled
rolling
Funding
—
unknown
Start date
flexible
Full-time
Location
Baltimore
United States

Overview

The University of Maryland, Baltimore is seeking a postdoctoral fellow specializing in computational protein design, structural bioinformatics, or machine learning. This role involves collaborating with experimental researchers to design and optimize therapeutic proteins and other molecular agents. The fellow will apply advanced computational methods to predict protein structures and analyze interactions, contributing to a vibrant research environment. Candidates are expected to present their findings and mentor junior researchers, fostering a collaborative atmosphere.

Protein DesignBioinformaticsMachine LearningComputational BiologyPythonMolecular Dynamics

What you'll do

  • Utilize protein structure prediction and design techniques to create candidate molecules.
  • Examine protein-protein interactions and the relationships between sequence, structure, and function.
  • Incorporate biological datasets to guide target selection and molecular design.
  • Work closely with experimental teams to validate computational predictions and integrate experimental data.
  • Provide computational and analytical support for the lab's research initiatives.
  • Share research findings at meetings and conferences, and prepare manuscripts for publication.
  • Guide and mentor junior researchers within the lab.

Requirements

Degree required: PhD in Computational Biology, Bioinformatics, Biophysics, Chemistry, Computer Science, or a related field

Language: English; proficiency required

Instruction: English

Publications: A record of publications in high-impact journals is preferred

Required skills
  • Experience with protein structure prediction tools like AlphaFold2/AlphaFold3 and Rosetta
  • Proficiency in Python and scientific computing
  • Familiarity with molecular dynamics simulation software such as GROMACS or AMBER
  • Ability to analyze protein-ligand interactions and high-throughput sequencing datasets
Nice to have
Experience with deep mutational scanning or directed evolutionA proven track record of computational designs validated through experimentsStrong communication and writing abilities

Funding & terms

Type
Unknown
Amount
—
Duration
unknown
Programme
—

How to apply

Interested candidates should submit their CV, a cover letter detailing their research experience and interest in the position, along with contact information for three references.

Documents required
  • CV
  • Cover letter
  • Contact information for three references
✉Apply by email

Contact

Nalinikanth Kotagiri· Supervisor

NKotagiri@som.umaryland.edu

NK
Prof.
Nalinikanth Kotagiri
Division of Pulmonary, Critical Care and Sleep Medicine
Lab
Division of Pulmonary, Critical Care and Sleep Medicine
University of Maryland Baltimore
United States
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