PhD Research Fellow in Computational Medicinal Chemistry
Investigate the structural and functional impacts of opioid receptor mutations using high-performance molecular simulations.
Best for:Best for candidates with a Master's degree in computational chemistry, structural biology, or related fields, and experience in molecular dynamics simulations.
Overview
The Department of Pharmacy at the University of Oslo invites applications for a PhD Research Fellow position in computational structural biology. Operating within the interdisciplinary 'DECODING ADDICTION' project, the successful candidate will examine the structural consequences of the R181C mutation in the mu-opioid receptor using advanced computational chemistry. The research environment integrates computational modeling, neuroscience, and molecular biology, utilizing high-performance GPU computing via the LUMI supercomputer. The candidate will be expected to conduct independent molecular simulations, collaborate with multidisciplinary team members, and contribute to scientific publications.
What you'll do
- Perform state-of-the-art molecular dynamics simulations to analyze opioid receptor variants
- Utilize high-performance computing resources, including the LUMI supercomputer, for intensive computational tasks
- Analyze structural and functional consequences of the R181C mutation in the mu-opioid receptor
- Collaborate across disciplinary boundaries with researchers in neuroscience, molecular biology, and psychology
- Prepare research findings for publication in peer-reviewed scientific journals and present results at conferences
Requirements
Degree required: Master Degree or equivalent
Degree offered: PhD
Language: English; strong written and verbal proficiency
Instruction: English
- Background in computational chemistry, structural biology, or a closely related discipline
- Experience with molecular dynamics simulations and computational modeling tools
- Ability to handle large-scale computational workloads on high-performance computing systems
- Strong analytical and problem-solving skills
- Must hold a Master's degree or equivalent in a relevant field by the appointment date
Funding & terms
How to apply
Deadline: 2026-11-09 (Europe/Oslo)
Interested applicants must submit their application materials through the designated external job portal link provided in the vacancy notice. Ensure all required documents are uploaded prior to the application deadline.
- CV
- Cover letter
- Transcripts
- Master's thesis
Contact
Osman Gani / T. V. Hansen
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