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Senior Researcher / Lead Researcher - Immuno-Oncology

Drive preclinical immuno-oncology modeling and therapeutic studies at St. Jude Children's Research Hospital.

Best for:Best for experienced researchers with a strong background in murine cancer models, in vivo therapeutic studies, and preclinical immuno-oncology workflows.

St Jude Children's Research Hospital · Memphis, United States · R2 · Recognised researcher
More professors at St Jude Children's Research Hospital
Immuno-OncologyPreclinical ModelingCancer BiologyTranslational ResearchIn Vivo Studies
This is a research staff position — not a PhD studentship.
Deadline
Nov 20, 2026
34 days
Funding
Salaried
$60.3k–$105.0k/yr
Start date
flexible
Permanent
Location
Memphis
United States

Overview

The Center of Excellence for Pediatric Immuno-Oncology (CEPIO) at St. Jude Children's Research Hospital is seeking a Senior or Lead Researcher to join its immuno-oncology modeling core. The successful candidate will independently execute preclinical in vivo studies, perform complex murine procedures, and conduct cellular and molecular laboratory assays to support pediatric cancer research. This role involves designing and maintaining experimental workflows, documenting study progress, and collaborating with cross-disciplinary teams to translate innovative therapies. Applicants will work under the direction of the CEPIO I-O modeling core head to ensure efficient study execution, data integrity, and protocol optimization.

Immuno-oncologyMurine cancer modelsPreclinical researchIn vivo studiesLead researcherSenior researcherFlow cytometryTranslational medicine

What you'll do

  • Independently perform preclinical in vivo studies using established or modified experimental protocols.
  • Execute assigned study activities, including animal scheduling, treatments, procedures, sample collection, and study endpoints.
  • Perform murine procedures for preclinical cancer studies, including tumor implantation, therapeutic administration via multiple routes, survival procedures, and blood or tissue collection.
  • Conduct wet-laboratory procedures supporting preclinical studies, such as cell culture, tumor cell preparation, tissue processing, PCR/genotyping, and molecular or immune-related assays.
  • Monitor murine health and study progress, accurately document procedures and observations, and organize experimental data.
  • Maintain organized schedules and records for multiple concurrent studies while collaborating with animal facility staff.
  • Contribute to the development, optimization, and documentation of laboratory procedures and standard operating procedures.
  • Provide technical guidance and training to less experienced team members in established laboratory practices.

Requirements

Degree required: Bachelor's degree in a relevant scientific area

Language: English

Instruction: English

Required skills
  • Hands-on experience with murine cancer models or preclinical therapeutic studies
  • Experience performing rodent procedures including tumor implantation, therapeutic administration, and survival surgeries
  • Proficiency in wet-laboratory procedures such as cell culture, tissue processing, and molecular assays
  • Ability to monitor murine health, manage animal scheduling, and maintain detailed experimental records
  • Strong understanding of research and development methods in a laboratory setting
Nice to have
Experience with genetically engineered mouse models including breeding and genotypingExperience with immuno-oncology therapeutic evaluation and biomarker analysisFamiliarity with complex murine studies involving multiple treatment groups and collection time pointsPrior experience in translational research and preclinical cancer investigation
Eligibility
  • Lead Researcher: 5+ years of research experience, or 3+ years with a Master's degree, or a PhD with no prior experience required.
  • Senior Researcher: 2 years of research experience, or a Master's degree with no prior experience required.

Funding & terms

Type
Salaried
Amount
$60.3k–$105.0k/yr
Duration
—
Programme
St Jude Children's Research Hospital
St Jude Children's Research Hospital

How to apply

Deadline: 2026-11-20

Submit your application through the official career portal by the specified deadline. Ensure all required professional documents and qualifications are included for review.

Documents required
  • CV
  • Cover letter
↗Apply on site
Lab
CEPIO I-O Modeling Core
St Jude Children's Research Hospital
United States
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