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Biomedicine and Infectious Diseases● OpenPreview

PhD Position in Advanced HIV-1 Reservoir Diagnostics

Join Karolinska Institutet for a PhD investigating HIV-1 reservoirs using advanced proviral sequencing and bioinformatics.

Best for:Best for biomedical laboratory scientists with a strong background in molecular virology, sequencing, and bioinformatics.

Karolinska Institutet · Stockholm, Sweden · R1 · First-stage researcher
More professors at Karolinska Institutet
HIV-1 reservoirsMolecular virologyBioinformaticsProviral DNATranslational medicine
Deadline
Nov 13, 2026
21 days
Funding
Salaried
4 years
Start date
flexible
Fixed-term
Location
Stockholm
Sweden

Overview

Karolinska Institutet offers a four-year full-time doctoral position focusing on the development and implementation of advanced HIV-1 reservoir diagnostics. Based within the research team of Maarten van de Klundert at the Department of Medicine, Huddinge, the candidate will combine clinical sampling with molecular and bioinformatic analyses of HIV-1 proviruses. The position is part of the national BioLabX graduate school, which provides structured training and interdisciplinary collaboration opportunities. The successful candidate will be expected to establish workflows for proviral DNA characterization, handle clinical biobanking, and study immunological characteristics.

PhDHIV-1DiagnosticsBioinformaticsVirologyKarolinska InstitutetBiomedical Laboratory Science

What you'll do

  • Establish and optimize workflows for the analysis of HIV-1 proviral DNA to evaluate genetic diversity, viral subtypes, and drug-resistance mutations.
  • Conduct advanced bioinformatics and phylogenetic analyses on sequencing data from clinical cohorts.
  • Manage biobanking activities for incoming clinical samples and participant materials.
  • Characterize immunological parameters of study participants using methods such as FACS and ELIspot assays.
  • Fulfill all coursework, seminar, and training requirements associated with the Karolinska Institutet doctoral program and BioLabX graduate school.

Requirements

Degree required: Master's degree or equivalent in Biomedical Laboratory Science or a related field

Degree offered: PhD

Language: English; proficiency equivalent to Swedish upper secondary school English B / English 6

Instruction: English

Required skills
  • Degree in Biomedical Laboratory Science or an equivalent qualification
  • Strong interest in HIV research, molecular virology, and translational medicine
  • Good analytical skills for interpreting experimental and quantitative datasets
  • Demonstrated ability to work collaboratively in a multidisciplinary environment
Nice to have
Experience with experimental laboratory work in molecular biology, microbiology, or virologyHands-on experience with DNA and RNA sequencing, especially NGS and phylogeneticsBasic programming and bioinformatics skills using R, Python, or Linux environmentsFamiliarity with immunological methods such as PBMC isolation, FACS, and ELIspot assays
Eligibility
  • Must be a graduated biomedical laboratory scientist to meet BioLabX graduate school criteria
  • Must meet the general and specific university eligibility requirements for doctoral education at Karolinska Institutet

Funding & terms

Type
Salaried
Amount
—
Duration
4 years
Programme
BioLabX Graduate School
Karolinska Institutet

How to apply

Deadline: 2026-11-13

Submit your complete application, including a personal letter and curriculum vitae, through the Varbi recruitment system before the deadline. Ensure all academic transcripts and eligibility documents are attached according to the university guidelines.

Documents required
  • CV
  • Personal letter
  • Degree certificates and transcripts
  • Degree projects and previous publications
  • Eligibility documentation
↗Apply on site

Contact

MV
Prof.
Maarten van de Klundert
Department of Medicine, Huddinge
Lab
Maarten van de Klundert Research Team
Karolinska Institutet
BioLabX Graduate SchoolSweden
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