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Neurosciences● OpenPreview

PhD Opportunity: Gene Therapy & Genome Editing for Hearing Disorders

Join a pioneering project in gene therapy for hearing disorders at Institut Pasteur.

Best for:Best for ambitious scientists eager to innovate in gene therapy and genome editing.

Institut Pasteur · Paris, France · R1 · First-stage researcher
More professors at Institut Pasteur
gene therapygenome editingneuroscienceCRISPRsensory functionbiomedical research
Deadline
Oct 31, 2026
17 days
Funding
—
Temporary
Start date
flexible
Full-time
Location
Paris
France

Overview

The Institut Pasteur in Paris is seeking a highly motivated PhD candidate for the RESTORE project, which focuses on developing advanced AAV gene therapy and precision genome editing techniques for Usher syndrome. This role involves utilizing unique humanized mouse models to explore therapeutic efficacy and safety in restoring inner ear function. The successful applicant will receive multidisciplinary training in gene therapy, CRISPR technology, and sensory neuroscience within a renowned research environment. Candidates with a strong academic background in molecular biology, neuroscience, genetics, or biotechnology are encouraged to apply.

PhDgene therapygenome editingUsher syndromemolecular biologyneurosciencebiotechnologyCRISPR

What you'll do

  • Conduct research on gene therapy and genome editing for hearing disorders.
  • Utilize humanized mouse models to assess therapeutic efficacy.
  • Investigate intervention timing and long-term safety of treatments.
  • Collaborate with a multidisciplinary team in a research environment.
  • Engage in advanced imaging and functional phenotyping.

Requirements

Degree required: Master's degree in molecular biology, neuroscience, genetics, biotechnology, or a related field

Degree offered: PhD

Language: English; proficiency required

Instruction: English

Required skills
  • Strong academic record in relevant fields
  • Experience in molecular/cell biology or genetics
  • Ability to conduct rigorous scientific research
  • Curiosity and motivation to solve complex biomedical problems
Nice to have
Prior experience in gene therapy or genome editingFamiliarity with advanced imaging techniquesKnowledge of sensory neuroscience
Eligibility
  • Open to all nationalities
  • Must hold a Master's degree or equivalent

Funding & terms

Type
Unknown
Amount
—
Duration
Temporary
Programme
Not funded by a EU programme

How to apply

Deadline: 2026-10-31 (Europe/Paris)

Interested candidates should apply via email to the supervisors listed. Additionally, applications can be submitted through the provided website link.

Documents required
  • CV
  • Cover letter
  • Research proposal
↗Apply via form

Contact

AE
Prof.
Aziz El-Amraoui
Institut reConnect
Lab
Institut reConnect
Institut Pasteur
Not funded by a EU programmeFrance
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