PhD Position in Vascular Biology and Endothelial Repair

This PhD project at the University of Toulouse investigates the cellular and molecular mechanisms governing vascular homeostasis and endothelial repair, with a specific focus on the purinergic receptor P2Y1. Cardiovascular diseases remain a leading global cause of mortality, and understanding endothelial dysfunction is critical for developing new therapeutic strategies. The successful candidate will utilize genetically modified mouse models and molecular biology approaches to examine endothelial P2Y1 signaling and its role in protecting against atherosclerosis. The researcher will be expected to conduct experiments, analyze immunohistological data, and contribute to scientific publications.

• Perform experiments using genetic mouse models to study endothelial P2Y1 receptor function in vivo.
• Conduct immunohistological analyses to evaluate endothelial injury and repair mechanisms.
• Investigate cellular signaling pathways utilizing molecular biology techniques on cultured endothelial cells.
• Analyze, interpret, and present experimental data within the research group.
• Contribute to writing scientific reports, papers, and participating in lab meetings.