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Health and Computer Sciences● OpenResearch staffPreview

Technical Lead, Medicines Safety Technologies

Provide senior scientific and technical leadership for AI and medicines safety initiatives at the MHRA.

Best for:Best for experienced professionals with a background in AI, machine learning, toxicology, or healthcare data science looking to lead regulatory science initiatives.

The Medicines And Healthcare Products Regulatory Agency · London, United Kingdom · R3 · Established researcher
More professors at The Medicines And Healthcare Products Regulatory Agency
Artificial IntelligenceMedicines SafetyToxicologyPharmacologyHealthcare Data ScienceRegulatory Science
This is a research staff position — not a PhD studentship.
Deadline
Nov 15, 2026
24 days
Funding
Salaried
£78.2k–£87.8k/yr
Start date
flexible
Full-time
Location
London
United Kingdom

Overview

The Medicines and Healthcare Products Regulatory Agency (MHRA) is seeking an experienced Technical Lead to join the Benefit/Risk Evaluation Team within the Safety and Surveillance group. The successful candidate will provide senior scientific and technical leadership for the 'Beyond ADMET: AI for Medicines Safety' Sandbox programme, ensuring activities are scientifically robust and aligned with regulatory objectives. Responsibilities include leading the evaluation of emerging methodologies, datasets, and AI-enabled technologies, while building strategic partnerships across industry, academia, and government. Applicants are expected to possess significant expertise in artificial intelligence, toxicology, pharmacology, or healthcare data science, alongside a strong record of translating scientific evidence into practical regulatory recommendations.

Technical LeadAI for Medicines SafetySandbox ProgrammeBenefit Risk EvaluationRegulatory ScienceMachine LearningToxicologyPharmacology

What you'll do

  • Provide senior scientific and technical leadership for the 'Beyond ADMET: AI for Medicines Safety' Sandbox programme.
  • Ensure all programme activities remain scientifically robust, technically credible, and aligned with regulatory objectives.
  • Partner with the Head of AI for Medicines Safety to integrate multidisciplinary expertise across artificial intelligence, healthcare data science, and pharmacology.
  • Lead the evaluation of emerging methodologies, technologies, datasets, and evidence relevant to AI-enabled medicines development and safety assessment.
  • Build and maintain collaborative relationships with internal experts, industry partners, academic institutions, and government bodies.
  • Represent the programme through technical engagement, stakeholder collaboration, and thought leadership activities.
  • Translate complex scientific findings into practical recommendations, technical reports, briefings, and regulatory submissions.

Requirements

Degree required: Degree in a relevant scientific, technical, or healthcare discipline (or equivalent experience), accompanied by a postgraduate qualification (MSc, PhD, or equivalent experience) in a related field.

Language: English; professional proficiency

Instruction: English

Required skills
  • Recognized technical expertise in pharmacology, toxicology, drug development, safety science, New Approach Methodologies (NAMs), artificial intelligence, machine learning, or healthcare data science.
  • Ability to critically evaluate complex scientific evidence, AI methodologies, model performance, and validation approaches.
  • Demonstrated experience applying scientific and technical expertise to complex regulatory, healthcare, research, or industry challenges.
  • Experience working effectively within multidisciplinary teams involving scientific, technical, and non-technical stakeholders.
  • Proven track record of preparing technical reports, scientific assessments, briefings, publications, or regulatory submissions.
Nice to have
Experience engaging directly with external stakeholders across academia, industry, and research organizations.Familiarity with pre-clinical assessment and computational modeling in drug discovery.
Eligibility
  • Must have the right to work in the United Kingdom.

Funding & terms

Type
Salaried
Amount
£78.2k–£87.8k/yr
Duration
permanent
Programme
UK Civil Service
UK Civil Service

How to apply

Deadline: 2026-11-15

Submit your application through the official Civil Service Jobs portal by the specified closing date. Ensure all required documentation demonstrating your technical expertise and professional experience is attached.

Documents required
  • CV
  • Cover letter
↗Apply on site
Lab
Medicines Safety Technologies
The Medicines And Healthcare Products Regulatory Agency
United Kingdom
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