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Pharmacology and Evolutionary Biology● OpenPostdoc⏰ 8 days leftPreview

Research Fellow in Pharmacology

Join an HFSP-funded project investigating the evolutionary origins of sensory receptors and ion channels.

Best for:Best for researchers with a background in molecular pharmacology, ion channel characterization, and an interest in evolutionary biology.

University of Southampton · Southampton, United Kingdom · R2 · Recognised researcher
More professors at University of Southampton
Molecular PharmacologyEvolutionary BiologySensory NeuroscienceIon ChannelsTRP ChannelsComparative Genomics
This is a postdoc position — not a PhD studentship.
Deadline
Oct 23, 2026
8 days
Funding
Salaried
£36.6k–£41.1k/yr
Start date
flexible
Fixed-term
Location
Southampton
United Kingdom

Overview

The University of Southampton is seeking a motivated Research Fellow to join an interdisciplinary project funded by the Human Frontier Science Program (HFSP). This role focuses on the evolutionary origins and functional characterization of sensory receptors, specifically Transient Receptor Potential (TRP) channels in non-bilaterian animals and choanoflagellates. The successful candidate will integrate molecular pharmacology with evolutionary biology, utilizing techniques such as molecular cloning, heterologous expression, and pharmacological assays. You will work within the School of Biological Sciences and collaborate with international partners, including a laboratory in France. The position offers a unique opportunity to contribute to fundamental questions regarding the evolution of animal sensation.

Research FellowPharmacologyMolecular BiologyIon ChannelsEvolutionary BiologyHFSPCell Biology

What you'll do

  • Perform molecular cloning and construct preparation for candidate sensory receptors.
  • Express candidate proteins in mammalian cell systems for functional characterization.
  • Develop and optimize functional assays for medium- to high-throughput pharmacological screening.
  • Conduct concentration-response experiments and quantitative data analysis to determine pharmacological properties.
  • Collaborate with international partners on sensory-driven behavior and channel function research.
  • Maintain accurate experimental records and ensure research reproducibility.
  • Communicate research findings through publications and conference presentations.

Requirements

Degree required: PhD in pharmacology, molecular biology, neuroscience, biochemistry, physiology, or evolutionary biology.

Language: English (professional proficiency).

Instruction: English

Required skills
  • Expertise in molecular biology, cloning, and construct preparation.
  • Experience with heterologous expression systems.
  • Proficiency in quantitative experimental data analysis and statistical methods.
  • Ability to work independently and within an interdisciplinary team.
Nice to have
Experience with mammalian cell culture and fluorescence- or luminescence-based assays.Familiarity with ion channels, GPCRs, or TRP channels.Experience with high-throughput screening or plate-reader-based assays.Proficiency in R or Python for data analysis.Experience with Xenopus oocyte expression or electrophysiology.
Eligibility
  • Must hold or be near completion of a PhD in a relevant discipline.

Funding & terms

Type
Salaried
Amount
£36.6k–£41.1k/yr
Duration
3 years
Programme
Human Frontier Science Program (HFSP)
Human Frontier Science Program

How to apply

Deadline: 2026-10-23

Interested candidates should submit their application through the official university portal. Ensure all required documentation is attached to support your candidacy.

Documents required
  • CV
  • Cover letter
↗Apply on site

Contact

LY
Prof.
Luis Yanez-Guerra
School of Biological Sciences
Lab
Neuroscience
University of Southampton
Human Frontier Science Program (HFSP)United Kingdom
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