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Immunology● OpenPreview

Doctoral (PhD) Student Position in Colorectal Tumor Immunology

Explore human mucosal immunology and colorectal cancer using single-cell RNA sequencing and spatial transcriptomics.

Best for:Best for life science graduates with a background in immunology, tissue processing, and bioinformatics.

Karolinska Institutet · Stockholm, Sweden · R1 · First-stage researcher
More professors at Karolinska Institutet
Tumor ImmunologySingle-Cell RNA SequencingMucosal ImmunologySpatial TranscriptomicsColorectal Cancer
Deadline
—
Funding
Salaried
4 years
Start date
flexible
Fixed-term
Location
Stockholm
Sweden

Overview

The Mjösberg group at Karolinska Institutet is offering a four-year fully funded doctoral position focused on mucosal immunology in colorectal cancer. The research involves investigating innate lymphoid cells and T cells using advanced single-cell RNA sequencing, multicolor flow cytometry, and spatial transcriptomics on clinical human tissue samples. The successful candidate will work within a multidisciplinary team to uncover novel disease mechanisms and biomarkers. In addition to conducting independent research, the PhD student will contribute to database management, lab duties, and student supervision.

PhDImmunologySingle-Cell RNA-seqFlow CytometryColorectal CancerKarolinska InstitutetTranslational Research

What you'll do

  • Isolate, culture, and process primary human immune cells from intestinal and tumor specimens.
  • Generate and process single-cell RNA sequencing and multicolor flow cytometry data.
  • Establish and perform in vitro lymphocyte differentiation assays and spatial transcriptomic analyses.
  • Manage, organize, and coordinate experimental databases and clinical datasets.
  • Collaborate closely with multidisciplinary teams and clinical staff.
  • Contribute to general laboratory maintenance and assist in supervising other students and researchers.

Requirements

Degree required: Master's degree in biomedicine, medicine, immunology, or a related field

Degree offered: PhD

Language: English; proficiency equivalent to Swedish upper secondary school English B / English 6

Instruction: English

Required skills
  • Experience with human tissue processing and primary human immune cell isolation and culture
  • Proficiency in single-cell RNA sequencing and bioinformatic analysis using R or Python
  • Strong organizational skills and ability to manage research datasets
  • Effective communication skills and proven ability to work in multidisciplinary teams
  • Fluency in English
Nice to have
Skills in multidimensional flow cytometric analysis and cell sorting exceeding 20 parametersExperience in logistical coordination of clinical or translational studiesBasic knowledge of Swedish or willingness to learn
Eligibility
  • Must hold a second-cycle qualification (Master's degree) or have completed at least 240 higher education credits with at least 60 credits at the advanced level by the position start date.

Funding & terms

Type
Salaried
Amount
—
Duration
4 years
Programme
Karolinska Institutet
Karolinska Institutet

How to apply

Submit your complete application through the Varbi recruitment system by using the online application button. Ensure all required academic transcripts, CV, and personal statements are attached before the submission deadline.

Documents required
  • CV
  • Personal letter
  • Degree projects and previous publications
  • Master's degree transcripts and certificates verifying general and specific eligibility
↗Apply on site
Lab
Mjösberg group
Karolinska Institutet
Sweden
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