Doctoral Researcher/Project Researcher in Molecular Physiology

The Molecular Physiology research group at the A.I. Virtanen Institute, University of Eastern Finland, is seeking a Doctoral or Project Researcher for a three-year position starting January 1, 2027. The successful candidate will engage in a project funded by the Research Council of Finland, aimed at understanding and targeting dysregulated transcription in cardiovascular disease. Responsibilities include generating human induced pluripotent stem cell (hiPSC) models, conducting proteomics and sequencing experiments, and collaborating with physiologists. Applicants should be motivated and capable of independent research in a fast-paced environment.

• Develop hiPSC-derived 2D and 3D models using CRISPR techniques.
• Create knock-in hiPSC lines for proteomics and ChIP-seq experiments.
• Characterize genetically modified cardiomyocytes through various analyses.
• Test candidate chemical inhibitors in relevant in vitro models.
• Conduct protein biochemistry and molecular biology experiments.
• Collaborate with physiologists to analyze cell phenotypes.
• Collect and analyze data, and prepare manuscripts for publication.
• Present research findings at lab meetings and conferences.