PhD Studentship in Neurodevelopmental Disorders and Transcriptional Regulation
Investigate the root causes of neurodevelopmental disorders using human stem cells and advanced genomics.
Best for:Best for life science graduates with an interest in stem cell biology, genomics, and neurodevelopmental disease mechanisms.
Overview
The University of Exeter, through the GW4 BioMed3 Doctoral Landscape Programme, is offering a funded four-year PhD studentship starting in October 2027. The research focuses on identifying early molecular triggers in neurodevelopmental conditions such as autism, intellectual disability, and epilepsy. The successful candidate will employ human stem cells, genome editing, and high-throughput genomics tools like CUT&Tag and RNA-seq to analyze chromatin and gene activity changes. The position provides comprehensive training in cutting-edge biomedical techniques within a collaborative research environment.
What you'll do
- Cultivate and differentiate human stem cells into early brain cell models.
- Perform genome editing and rapidly deactivate disease-linked transcription factors.
- Execute advanced genomics assays including CUT&Tag and RNA-seq to measure chromatin accessibility and gene activity.
- Analyze complex genomic datasets to uncover early disruptions in gene control mechanisms.
- Participate in doctoral training activities, research meetings, and present findings at scientific seminars.
Requirements
Degree required: BSc or MSc in a relevant biomedical, biological, or computational science discipline
Degree offered: PhD
Language: English
Instruction: English
- Background in molecular biology, genetics, or cellular biology
- Familiarity with standard molecular biology laboratory techniques
- Capacity to learn complex genomic and bioinformatics workflows
- Strong analytical and critical thinking abilities
- Open to UK and international students
- Must meet standard institutional entry requirements for doctoral study
Funding & terms
How to apply
Deadline: 2026-10-21
Candidates must review the project details and submit their application through the official university funding and admissions portal. Ensure all required academic transcripts, statements, and supporting references are prepared according to the GW4 BioMed3 guidelines.
- CV
- Cover letter
- Academic transcripts
- Reference letters
Contact
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