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Structural Biology and Neuroscience● OpenPreview

PhD Position in Structural Biology of Neuronal Exocytosis

Explore the molecular mechanisms of neurotransmitter release through cutting-edge structural biology techniques.

Best for:Best for candidates with a master's degree in biochemistry, structural biology, or molecular neuroscience, eager to contribute to fundamental research on synaptic transmission mechanisms.

Forschungszentrum Jülich · Jülich, Germany · R1 · First-stage researcher
More professors at Forschungszentrum Jülich
neuronal exocytosisSNARE protein complexesmembrane fusion mechanismsneurotransmitter releasestructural biology techniques
Deadline
Nov 4, 2026
22 days
Funding
—
Start date
flexible (expected soon after selection)
Full-time
Location
Jülich
Germany

Overview

This PhD position focuses on the structural biology of neuronal exocytosis, a critical process for neurotransmitter release. The successful candidate will join the Institute of Biological Information Processing at Forschungszentrum Jülich, working under expert supervision to investigate the assembly and function of SNARE protein complexes. The project combines advanced biochemical, biophysical, and structural biology methods to unravel the molecular intricacies of membrane fusion. Applicants should have a strong background in biological sciences, biochemistry, or related fields, with a keen interest in neuroscience and structural biology.

structural biologyneuroscienceSNARE complexesmembrane fusionbiochemical methodsbiophysical techniquesneurotransmissionprotein assembly

What you'll do

  • Investigate the structural and functional dynamics of SNARE protein complexes during neuronal exocytosis.
  • Apply advanced biochemical and biophysical techniques to study membrane fusion mechanisms.
  • Perform high-resolution structural analyses using cryo-electron microscopy or X-ray crystallography.
  • Develop and validate experimental models to elucidate the molecular basis of neurotransmitter release.
  • Collaborate with interdisciplinary teams to integrate findings into broader neuroscience research.
  • Present research findings at national and international conferences and publish results in peer-reviewed journals.

Requirements

Degree required: Master's degree in Biochemistry, Structural Biology, Molecular Neuroscience, or a related field

Degree offered: PhD

Language: English; proficiency sufficient for academic research and publication

Instruction: English

Required skills
  • Proven expertise in biochemical and biophysical techniques
  • Experience with structural biology methods (e.g., cryo-EM, X-ray crystallography)
  • Strong background in molecular biology and protein biochemistry
  • Familiarity with neuroscience research and synaptic transmission mechanisms
  • Excellent laboratory skills and attention to detail
Nice to have
Experience with advanced imaging techniques (e.g., cryo-electron microscopy)Knowledge of computational modeling and data analysis toolsPublication record in relevant scientific journalsFluency in scientific writing and presentation
Eligibility
  • No specific nationality restrictions
  • No age restrictions
  • No prior experience caps beyond a completed master's degree

Funding & terms

Type
Unknown
Amount
—
Duration
—
Programme
—

How to apply

Deadline: 2026-11-04 (Europe/Berlin)

Applicants should submit their application via the Forschungszentrum Jülich portal. The application package should include a cover letter, CV, academic transcripts, and a research proposal outlining their interest and qualifications for the position. Contact details for further inquiries are available on the Forschungszentrum Jülich website.

Documents required
  • Cover letter
  • Curriculum Vitae (CV)
  • Academic transcripts (BSc and MSc)
  • Research proposal (1-2 pages)
  • Letters of recommendation (if applicable)
↗Apply on site
Lab
Structural Biochemistry (IBI-7)
Forschungszentrum Jülich
Germany
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