Postdoctoral Fellow in Structural and Molecular Biology
Lead structural and functional studies of transcription enzymes using cryo-EM and X-ray crystallography at USC.
Best for:Best for molecular biologists and structural biologists with strong experience in cryo-EM or X-ray crystallography.
Overview
The laboratory of Dr. Xiaojiang Chen at the University of Southern California is seeking a fully funded Postdoctoral Research Associate to join their team in the Department of Molecular and Cellular Biosciences. The researcher will conduct structural and functional investigations of enzymes involved in DNA and RNA transcription related to cancer and infectious diseases. This role provides access to advanced cryo-EM and X-ray facilities, alongside opportunities for close collaboration with chemical biologists. The successful candidate is expected to independently lead experimental studies and contribute to uncovering critical functional mechanisms.
What you'll do
- Lead structural and functional studies focusing on enzymes involved in DNA and RNA transcription related to cancer and infectious diseases.
- Utilize advanced techniques such as cryo-EM, X-ray crystallography, biochemistry, and molecular biology.
- Collaborate closely with chemical biologists to elucidate functional mechanisms of target enzymes.
- Manage laboratory experiments and document research findings for publication in peer-reviewed journals.
- Utilize state-of-the-art core facilities for imaging and structural determination.
Requirements
Degree required: PhD in Structural Biology, Molecular Biology, or a related field
Language: English; professional proficiency
Instruction: English
Publications: Relevant peer-reviewed publication record appropriate for a postdoctoral candidate
- Demonstrated research experience in structural biology or molecular biology
- Hands-on expertise in cryo-EM or X-ray crystallography
- Strong background in biochemical assay design and protein characterization
- Track record of scientific publication in peer-reviewed journals
- Hold a completed PhD degree
Funding & terms
How to apply
Deadline: 2026-12-03
Interested applicants should submit their application materials through the designated careers portal or reach out according to the laboratory instructions provided on the official website.
- CV
- Cover letter
Contact
Xiaojiang Chen· Professor
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