PhD Monitor
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Computational Biology and Developmental Biology● OpenOpen until filledPreview

PhD Position in Digital Twins for Embryonic Development

Develop computational models of organogenesis using data-driven simulations and mechanistic approaches in an interdisciplinary research environment.

Best for:Best for candidates with a strong background in biology, mathematical modeling, and programming who are passionate about computational approaches to developmental biology.

ETH Zurich · Basel, Switzerland · R1 · First-stage researcher
More professors at ETH Zurich
digital twins in biologyorganogenesis modelingmechanistic computational modelingtissue self-organizationembryonic development simulations
Deadline
Until filled
rolling
Funding
Salaried
Competitive ETH doctoral salary and conditions
Start date
Flexible (exact date not specified)
Full-time
Location
Basel
Switzerland

Overview

This PhD position at ETH Zurich’s Computational Biology Group focuses on creating digital twins of embryonic development by integrating quantitative imaging data with mathematical and computational models. The project aims to understand tissue self-organization and disease mechanisms in mouse and human organogenesis. The successful candidate will collaborate closely with experimental biologists, publish findings, and contribute to open-source simulation tools. The work spans computational biology, mathematical modeling, and scientific programming, offering a unique interdisciplinary research experience in a leading Swiss institution.

digital twinembryonic developmentmathematical modelingcomputational biologyorganogenesismechanistic simulationquantitative imagingopen-source software

What you'll do

  • Develop data-driven, mechanistic models of tissue development using mathematical and computational approaches
  • Integrate quantitative imaging data from experimental collaborators into computational models
  • Publish research findings in international journals and present at conferences
  • Contribute to the group’s open-source simulation tools and software development
  • Collaborate with experimental biologists to validate and refine models
  • Participate in teaching and mentoring activities within the group

Requirements

Degree required: Master's degree in Biology, Computational Biology, Mathematics, Physics, Computer Science, or a related quantitative field

Degree offered: PhD

Language: English; proficiency required for academic communication and collaboration

Instruction: English

Required skills
  • Solid understanding of developmental, cell, and molecular biology
  • Experience with mathematical modeling (e.g., ordinary/partial differential equations, dynamical systems, or stochastic models)
  • Programming proficiency in Python, Julia, R, or MATLAB
  • Ability to interpret quantitative imaging and experimental data
  • Strong written and spoken English proficiency
Nice to have
Experience with finite element methods (e.g., COMSOL)Familiarity with C++ software developmentPrior exposure to open-source scientific software development
Eligibility
  • Open to all nationalities
  • No residency restrictions mentioned
  • No age or prior experience caps specified

Funding & terms

Type
Salaried
Amount
Competitive ETH doctoral salary and conditions
Duration
Fixed-term (exact duration not specified)
Programme
ETH Zurich
ETH Zurich

How to apply

Applicants must submit their application through ETH Zurich’s online application portal. Required documents include a letter of motivation, CV, BSc and MSc diplomas and transcripts, and contact details of two referees. Applications are reviewed on a rolling basis until the position is filled.

Documents required
  • Letter of motivation
  • CV
  • BSc diploma and transcript
  • MSc diploma and transcript
  • Contact details of 2 referees
↗Apply on site

Contact

DI
Prof.
Dagmar Iber
Department of Biology and Environmental Sciences (D-BSSE)
Lab
Computational Biology Group
ETH Zurich
Switzerland
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