Postdoctoral Fellow - AI-Enabled Immune Digital Twin Workflows
Build data-assimilating digital twin workflows and patient-specific forecasting pipelines in intelligent systems engineering.
Best for:Best for computational scientists with experience in mechanistic modeling, data assimilation, and Python software engineering.
Overview
Indiana University Bloomington invites applications for a postdoctoral position in intelligent systems engineering under the direction of Dr. James A. Glazier. The successful candidate will construct reproducible and testable sequential data-assimilating digital twin workflows for short-horizon forecasting and patient-specific rebasing. Responsibilities include designing anomaly-detection logic, managing complex model ensemble interfaces, and coordinating computational infrastructure with national consortium partners. The appointee will also engage in software engineering best practices, such as CI/CD and containerization, and contribute to technical publications.
What you'll do
- Develop Python workflows for short-horizon forecasting and patient-specific rebasing.
- Implement data-assimilation methods including Kalman and Bayesian updating.
- Design anomaly detection and missing-information inference logic.
- Build reproducible computational packages utilizing CI/CD, containers, and automated testing.
- Manage complex model ensemble interfaces and integrate workflows with external consortium platforms such as Vivarium and QSP.
- Coordinate computational infrastructure with national consortium collaborators and write technical publications.
Requirements
Degree required: PhD or equivalent terminal degree in a quantitative, computational, or biomedical discipline
Language: English
Instruction: English
- Programming proficiency in Python, Julia, R, or MATLAB
- Background in mechanistic modeling such as ODE, dynamical systems, QSP, or agent-based modeling
- Familiarity with inflammation, cytokine signaling, sepsis, or critical care biology
- Experience with data assimilation or sequential updating methods
Funding & terms
How to apply
Deadline: 2026-11-02
Interested candidates should submit their application materials through the designated external portal link. For any direct questions regarding the position, applicants may contact Professor James Glazier via email.
- CV
Contact
James Glazier· Professor
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