PhD Student in Stem Cell & Organoid Research
Investigate childhood leukemia and immune defects using iPSC-derived organoids and CRISPR screens.
Best for:Best for life science graduates with a master's degree and hands-on experience in molecular cloning, cell culture, or gene editing.
Overview
The Elisabeth Salzer Group at the St. Anna Children's Cancer Research Institute in Vienna is offering a PhD position focused on human lymphocyte development and pediatric cancer. The research combines induced pluripotent stem cells, advanced thymus and bone marrow organoid systems, and CRISPR-based genome engineering to study childhood leukemia and inborn errors of immunity. The successful candidate will work in a collaborative, international environment alongside clinicians and translational researchers. The role involves designing and optimizing organoid models, conducting genetic screens, and preparing research findings for publication.
What you'll do
- Generate and optimize lymphoid organoid systems derived from induced pluripotent stem cells and primary human CD34+ cells
- Perform CRISPR screens targeting genes implicated in human lymphocyte development
- Generate and characterize lymphocyte organoid cultures from CRISPR-edited CD34+ stem cells
- Monitor scientific literature and integrate new experimental approaches into ongoing projects
- Analyze experimental data, prepare manuscripts for publication, and present results at internal meetings and international conferences
Requirements
Degree required: Master's degree in Immunology, Cell Biology, Molecular Biology, a related field or MD in human Medicine
Degree offered: PhD
Language: English; proficiency required for scientific communication and writing
Instruction: English
Publications: List of publications if applicable, with an explanation of top contributions
- Hands-on lab experience in molecular cloning, CRISPR editing, cell culture, or single cell sequencing
- Rigor and attention to detail in experimental design and data analysis
- Ability to work independently as well as part of a collaborative international team
Funding & terms
How to apply
Deadline: 2026-10-15 · open until filled
Prepare your curriculum vitae, a cover letter detailing your motivation for pursuing a PhD in this specific group, contact details for one reference, and a list of publications if applicable. Submit your application materials through the online application portal before the deadline. Applications will be reviewed on a rolling basis until the position is filled.
- CV
- Cover letter
- Contact details of one reference
- List of publications
Contact
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