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Chemistry and Biochemistry● OpenPostdocPreview

Postdoctoral Research Associate in Natural Product Chemistry

Lead a biochemical research project exploring natural antifungal products derived from bdelloid rotifers.

Best for:Best for chemistry and biochemistry PhD graduates with laboratory experience in natural product isolation, structural elucidation, or synthetic biology.

University of Oxford · Oxford, United Kingdom · R2 · Recognised researcher
More professors at University of Oxford
natural productsantifungal chemistrybiosynthetic pathwayschemical biologybioactivity-guided extraction
This is a postdoc position — not a PhD studentship.
Deadline
Nov 11, 2026
23 days
Funding
Salaried
£39.4k–£44.0k/yr
Start date
2027-01-01
Full-time
Location
Oxford
United Kingdom

Overview

The University of Oxford seeks a Postdoctoral Research Associate to join the Oxford Martin Programme on Safer Antifungals. Working across the Life and Mind Building and the Department of Pharmacology, the successful candidate will lead a biochemical project focusing on natural antifungal products extracted from microscopic freshwater animals. The role involves bioactivity-guided extraction, structure elucidation, biosynthetic investigation, and chemical diversification. The appointee will collaborate within an interdisciplinary team bridging biology, chemistry, and medicine to translate discoveries into clinical and agricultural applications.

Postdoctoral Research AssociateNatural Product ChemistryBiochemistrySynthetic BiologyAntifungal CompoundsUniversity of Oxford

What you'll do

  • Perform bioactivity-guided extraction and purification of antifungal compounds from biological mixtures
  • Elucidate chemical structures and investigate mechanisms of action for biologically active molecules
  • Investigate biosynthetic origins, candidate pathways, and chemical or biosynthetic diversification of hit compounds
  • Conduct biological activity and toxicity assays to evaluate candidate antifungal agents
  • Write scientific publications and communicate research outcomes for academic audiences and future translation

Requirements

Degree required: PhD in chemistry, biochemistry, biosynthetic chemistry, or a related area of chemical biology

Language: English

Instruction: English

Required skills
  • Strong research expertise and specialist knowledge in chemistry, biochemistry, or chemical biology
  • Prior laboratory experience in purifying chemicals from complex biological mixtures
  • Demonstrated experience in structural elucidation of biologically active molecules
  • Familiarity with genetic and synthetic-biology approaches to natural product synthesis
  • Ability to show initiative in developing research ideas and methodologies
  • Excellent written and verbal communication skills
  • Proven capability to work effectively within a multidisciplinary team and advise other team members
Nice to have
Strong interest or experience in research translation and innovationExperience in biosynthetic pathway elucidation and reconstruction of bioactive molecules

Funding & terms

Type
Salaried
Amount
£39.4k–£44.0k/yr
Duration
36 months
Programme
Oxford Martin Programme on Safer Antifungals
Oxford Martin School

How to apply

Deadline: 2026-11-11

Applications must be submitted online through the University of Oxford e-recruitment system. Applicants are required to upload a CV and a supporting statement detailing their qualifications and research background.

Documents required
  • CV
  • Supporting statement
↗Apply on site
Lab
Oxford Martin Programme on Safer Antifungals
University of Oxford
Oxford Martin Programme on Safer AntifungalsUnited Kingdom
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