PhD Monitor
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Computational Biology● OpenOpen until filledPreview

PhD Position in Computational Methods for Digital Twins of Embryonic Development & Disease

Develop algorithmic infrastructure and simulation environments for digital twins of biological systems.

Best for:Best for candidates with a strong background in computational science, applied mathematics, or computer science and an interest in biological modeling.

ETH Zurich · Basel, Switzerland · R1 · First-stage researcher
More professors at ETH Zurich
Digital TwinsComputational ModelingMachine LearningBayesian InferenceUncertainty QuantificationEmbryonic Development
Deadline
Until filled
rolling
Funding
Salaried
Competitive ETH doctoral salary
Start date
flexible
Full-time
Location
Basel
Switzerland

Overview

The Computational Biology Group at ETH Zurich is seeking a PhD candidate to advance the development of digital twins for embryonic development and reproductive health. The role involves creating robust algorithmic infrastructure to handle nonlinear, high-dimensional models and complex simulations. You will work in an interdisciplinary team of modellers, experimentalists, and clinicians to improve parameter estimation, uncertainty quantification, and software scalability. The position offers the opportunity to contribute to open-source tools while applying advanced computational methods to real-world biomedical challenges.

Computational BiologyScientific ComputingPhysics-Informed Neural NetworksParameter EstimationSimulation SoftwareBiomedical Modeling

What you'll do

  • Develop and benchmark algorithms for parameter estimation and uncertainty quantification.
  • Implement and optimize physics-informed neural networks and machine learning approaches for biological models.
  • Maintain and extend the group's open-source simulation environment for performance and reproducibility.
  • Collaborate with experimentalists and clinicians to apply computational methods to hormonal cycle and IVF treatment models.
  • Publish research findings in peer-reviewed journals and present at international conferences.
  • Contribute to the group's teaching activities and open-source software development.

Requirements

Degree required: Master's degree in Computer Science, Computational Science and Engineering, Applied Mathematics, Physics, or a related field.

Degree offered: PhD

Language: Good written and spoken English.

Instruction: English

Required skills
  • Strong programming proficiency in Python, Julia, or C++.
  • Experience in writing clean, well-tested, and maintainable code.
  • Solid foundation in numerical methods, optimization, or statistical inference.
  • Demonstrated ability to work on data-based modeling projects.
  • Fluency in written and spoken English.
Nice to have
Experience with PDE-based simulations or finite element methods.Familiarity with high-performance computing environments.Proficiency in deep-learning frameworks such as PyTorch or JAX.

Funding & terms

Type
Salaried
Amount
Competitive ETH doctoral salary
Duration
fixed-term
Programme
ETH Zurich
ETH Zurich

How to apply

Applications must be submitted exclusively through the official ETH Zurich online portal. Please prepare a letter of motivation, your CV, academic transcripts, and contact details for two referees.

Documents required
  • Letter of motivation
  • CV
  • BSc diploma and transcripts
  • MSc diploma and transcripts
  • Contact details of 2 referees
↗Apply on site

Contact

DI
Lab
Computational Biology Group
ETH Zurich
Switzerland
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