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Biological Sciences● Open⏰ 0 days leftPreview

PhD Position: Regulatory T Cell Fitness and Inflammation

Investigate how IL-6 signaling shapes regulatory T cell fitness and function during tissue inflammation.

Best for:Best for ambitious life sciences graduates with a strong background in immunology and a desire to pursue cutting-edge molecular research.

International PhD Programme (IPP) Mainz · Mainz, Germany · R1 · First-stage researcher
More professors at International PhD Programme (IPP) Mainz
Regulatory T cellsImmunologyInflammationInterleukin-6 signalingMolecular biology
Deadline
Oct 15, 2026
0 days
Funding
Salaried
Fully funded positions with financing until the completion of your thesis
Start date
2027-02-01
Full-time
Location
Mainz
Germany

Overview

The International PhD Programme (IPP) Mainz, hosted at the Institute of Molecular Biology, invites applications for a fully funded doctoral position in the research group of Ilgiz Mufazalov in collaboration with Ari Waisman. The project explores how interleukin-6 signaling regulates the survival, stability, and suppressive functions of Foxp3+ regulatory T cells in inflammatory environments. The successful candidate will employ advanced mouse models, multicolor flow cytometry, and sequencing techniques to uncover key cellular and molecular mechanisms of immune tolerance. This position offers a vibrant, international research environment with comprehensive advanced training and access to state-of-the-art core facilities.

PhDTreg cellsImmunologyIL-6Flow cytometryMouse modelsInflammation

What you'll do

  • Conduct experimental research using mouse models of cytokine overproduction and deficiency
  • Perform multicolor flow cytometry and cell sorting analyses
  • Execute regulatory T cell transfer experiments to investigate survival and suppressive functions
  • Apply sequencing approaches to study transcriptional and epigenetic mechanisms
  • Collaborate with interdisciplinary team members and participate in institute scientific meetings

Requirements

Degree required: Master degree or equivalent in Life Sciences or related field

Degree offered: PhD

Language: English; good command required

Instruction: English

Required skills
  • Demonstrated background in immunology or molecular biology
  • Familiarity with or strong willingness to learn experimental mouse models
  • Interactive personality with good teamwork skills
Nice to have
Prior hands-on experience with flow cytometry or FACSPrevious exposure to immunological assay techniques or sequencing data analysis
Eligibility
  • Hold or be about to complete a Master degree or equivalent

Funding & terms

Type
Salaried
Amount
Fully funded positions with financing until the completion of your thesis
Duration
Duration of PhD thesis
Programme
International PhD Programme Mainz
International PhD Programme Mainz

How to apply

Deadline: 2026-10-15 (Europe/Berlin)

Interested applicants must submit their application through the online IPP application platform, ensuring they select Mufazalov/Waisman as their group preference. Candidates are also required to arrange for two letters of reference to be submitted.

Documents required
  • CV
  • 2 reference letters
↗Apply via form

Contact

IM
Prof.
Ilgiz Mufazalov
Institute of Molecular Biology
Lab
Ilgiz Mufazalov and Ari Waisman Group
International PhD Programme (IPP) Mainz
Germany
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