Postdoctoral Research Fellow - Fischer Lab
Investigate protein homeostasis and the ubiquitin proteasome system using structural and chemical biology approaches.
Best for:Best for structural biologists and biochemists with strong experience in protein expression, purification, and macromolecular structure determination.
Overview
The Fischer Lab at Dana-Farber Cancer Institute and Harvard Medical School is seeking a Postdoctoral Research Fellow to join an interdisciplinary team. The role focuses on biochemistry and structural biology projects addressing fundamental questions about the ubiquitin system and protein homeostasis. The successful candidate will leverage state-of-the-art facilities, including cryo-EM, X-ray crystallography, and mass spectrometry, to uncover mechanistic principles of cell signaling. Applicants are expected to lead complex structural biology projects, analyze data, and contribute to scientific publications.
What you'll do
- Design and execute advanced biochemistry and structural biology experiments focused on the ubiquitin proteasome pathway.
- Perform recombinant protein expression and purification using insect or mammalian systems.
- Collect and analyze high-resolution experimental data utilizing techniques such as cryo-EM, X-ray crystallography, or mass spectrometry.
- Prepare manuscripts for peer-reviewed research publications and present findings at scientific meetings.
- Collaborate effectively with an interactive multidisciplinary team of scientists, postdocs, and students.
Requirements
Degree required: PhD or equivalent degree in structural biology, biochemistry, biophysics, or molecular biology
Language: English; excellent oral and written capabilities
Instruction: English
Publications: Ability to prepare and contribute to research publications
- Proven ability to plan and execute complex structural biology projects.
- Experience in recombinant protein expression and purification.
- Proficiency in data collection and structure determination via X-ray crystallography or cryo-EM.
- Demonstrated ability to collect, analyze, and interpret experimental data.
- Strong written and oral communication skills for publishing research results.
- Must hold a recent PhD or equivalent in a relevant discipline.
Funding & terms
How to apply
Deadline: 2026-11-17
Submit your application through the official careers portal by providing the requested professional documents and personal details before the deadline.
- CV
- Cover letter
Contact
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