PhD opportunity - RNA Polymerase II Citrullination

The Institute of Pharmacology and Structural Biology (IPBS) in Toulouse, France, is seeking a motivated PhD candidate as part of the BEST Doctoral Programme of the University of Toulouse. The research project focuses on investigating RNA Polymerase II citrullination as a regulator of transcriptional control in triple-negative breast cancer. The successful candidate will be jointly supervised by Dr. Priyanka Sharma at IPBS and Dr. Juan Torreño Piña at the National Center for Biotechnology in Madrid, with additional collaboration at the Robert Bosch Center for Tumor Diseases. The student will engage in advanced molecular and cellular biology approaches to uncover novel pharmacological targets in cancer biology.

• Conduct cutting-edge research on RNA Polymerase II citrullination and its role in transcriptional regulation within triple-negative breast cancer models.
• Utilize molecular and cellular biology techniques alongside in vivo or experimental approaches.
• Collaborate closely with international partner institutions including the National Center for Biotechnology in Madrid and the Robert Bosch Center for Tumor Diseases.
• Analyze chromatin profiling data and integrate findings into the broader context of cancer epigenetics.
• Prepare scientific reports, present research findings at international conferences, and contribute to peer-reviewed publications.